PRIMA is a series of workshops on agent computing and multi-agent systems, integrating the activities in Asia and Pacific Rim countries. Agent computing and multi-agent systems are computational systems in which several autonomous or se- autonomous agents interact with each other or work together to perform some set of tasks or satisfy some set of goals. These systems may involve computational agents that are homogeneous or heterogeneous, they may involve activities on the part of agents having common or distinct goals, and they may involve participation on the part of humans and intelligent agents. The aim of PRIMA 2006 was to bring together Asian and Pacific Rim researchers and developers from academia and industry to report on the latest technical advances or domain applications and to discuss and explore scientific and practical problems as raised by the participants. PRIMA 2006 received 203 submitted papers. Each paper was reviewed by two internationally renowned Program Committee members. After careful reviews, 39 regular papers and 57 short papers were selected for this volume. We would like to thank all the authors who submitted papers to the workshop. We are very grateful to all Program Committee members and reviewers for their splendid work in reviewing the papers. Finally, we thank the editorial staff of Springer for publishing this volume in the Lecture Notes in Artificial Intelligence series.