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Industrial Process Scale-Up

Autor Jan Harmsen
en Limba Engleză Paperback – apr 2027
Industrial Product and Process Scale-up: A Practical Innovation Guide from Idea to Commercial Implementation, Third Edition serves as a comprehensive guide for all aspects of process and product scale-up from idea generation, through R&D, engineering, procurement, construction to implementation, providing insights on identifying and mitigating risks associated with commercial scale implementation - providing insights on identifying and mitigating risks associated with commercial scale implementation. The Third Edition introduces new strategies for product scale-up and integrating product and process scale-up across six innovation stages, offering methods for pilot plant decision-making, scale-down processes, and evaluation criteria for demo-plant versus commercial scale plant selection. Special emphasis is placed on unit operation scale-up methods and intensified process steps to aid decision-making during the feasibility stage, benefiting industries like pharma and active pharma ingredients. This book will be a valuable guide to researchers in industry, working to scale-up products and processes across commercial sectors. This book will also be a very useful guide to late-stage students and academics working in industrial chemical process engineering.
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Specificații

ISBN-13: 9780443414794
ISBN-10: 0443414793
Pagini: 350
Ediția:3rd edition
Editura: ELSEVIER SCIENCE

Notă biografică

Dr. Jan Harmsen is currently consultant of Harmsen Consultancy B.V. From 1996 to 2010 he was Principal Process Developer, Shell Technology Center Amsterdam. After thirty-three years of industrial experience in exploratory research, development, process design, and chemicals manufacturing, ir. Harmsen now successfully works as an independent consultant on innovation with sustainable development in view. He has published three books with Elsevier.


Cuprins

1. Introduction
2. Discovery stage
3. Concept stage
4. Feasibility stage
5. Development stage
6. Engineering Procurement Construction stage
7. Commercial scale implementation

Recenzii

"…will help industrial process innovators in research, development and commercial start-up to assess the risks of commercial-scale implementation and provide them with practical guidelines and methods to reduce the risks to acceptable levels…has a very clear, attractive layout, using text boxes that contain clarifying notes and additional information on specific topics…" --Water Conditioning & Purification, February 2014
"…a case study on amine absorption processes for CO2…is the best written chapter of all." --Organic Process Research & Development Journal, April 2014
"Writing for practitioners of industrial process design, the author presents technical and organizational guidance on the steps of process scale-up, from idea to implementation. He focuses in particular on risk reduction and increasing the chances of success. In addition to guidelines and methods, he includes case examples drawn from his own career in process development at Shell, as well as from publications by authors also experienced in industrial process scale-up." --ProtoView.com, February 2014