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Membrane Systems: For Bioartificial Organs and Regenerative Medicine de Loredana De Bartolo

Membrane Systems: For Bioartificial Organs and Regenerative Medicine

Autor Loredana De Bartolo, Efrem Curcio, Enrico Drioli
en Mixed media product – 14 feb 2016
The worldwide demand for organ transplants exceeds available donor organs by far. Understanding and controlling membrane material biocompatibility and transport phenomena currently opens new opportunities for the improvement of artificial organs (e.g., hemodialysis devices, hemofilters, blood oxygenator, etc.) and the design of bioartificial organs such as the bioartificial liver or pancreas. The book covers these topics and connects membrane systems to applications in regenerative medicine.
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Specificații

ISBN-13: 9783110268027
ISBN-10: 3110268027
Pagini: 360
Ilustrații: Includes a print version and an ebook
Dimensiuni: 170 x 240 mm
Ediția:
Editura: De Gruyter
Locul publicării:Berlin/Boston

Notă biografică

Loredana De Bartolo,University of Calabria, Rende, Italy; Efrem Curcio, University of Calabria, Rende, Italy; Enrico Drioli, University of Calabria, Rende, Italy.

Cuprins

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1. Natural and Synthetic Membranes

Biomedical Polymers

Preparation Techniques

Membrane Configurations

Characterization of Membrane Properties

Sterilization Procedures

2. Basic Issues in Membrane Separation for Biomedical Devices

Driving Forces in Molecular Separation

Transport through Microporous Membranes

Transport through Dense Membranes

Performance Parameters

3. Membrane Artificial Organs

Bioengineering Principles

Hemodialyser

Hemofilters

Plasmafilters

Blood Oxygenator

4. Biocompatibility Assessment

Membrane Trombogenicity

Complement Activation

Activation of Leukocytes

Inflammation Reaction

Bioincompatibility Aspects

5. Engineering of Membrane Biohybrid Organs

Modelling of Mass Transfer

Computational Fluid Dynamics Analysis

Analysis of Metabolic Kinetics

Configuration of Membrane Devices

6. Membrane Biohybrid Organs

Design Concepts

Liver

Pancreas

Kidney

Lung

Cardio-vascular devices

7. Citocompatibility Assessment

Cell Response

Protein Adsorption

Cell-Membrane Interactions

Role of Membrane Properties on Cell Arrangement and Organization

Evaluation of Tissue Compatibility

8. Regulatory and Ethical Issues

Regulatory of Biomedical Membrane Devices

Ethical Issues

Descriere

Descriere de la o altă ediție sau format:
The worldwide demand for organ transplants exceeds available donor organs by far. Understanding and controlling membrane material biocompatibility and transport phenomena currently opens new opportunities for the improvement of artificial organs (e.g., hemodialysis devices, hemofilters, blood oxygenator, etc.) and the design of bioartificial organs such as the bioartificial liver or pancreas.
The book covers the design and development of membranes and devices to be used as bio/artificial organs and in vitro growth of human cells as tissue engineered constructs, describes clinical applications of various membrane devices, bioengineering principles, materials and designs used in bio/artificial organs, and reviews the concepts, cell techniques, membrane scaffold materials and applications of tissue engineering.
An invaluable resource to researchers, scientists and academics involved in the advancement of membrane bio/artificial organs and tissues!