Hypoxia: Translation in Progress de Robert C. Roach

Hypoxia: Translation in Progress: Advances in Experimental Medicine and Biology, cartea 903

Editat de Robert C. Roach, Peter H. Hackett, Peter D. Wagner

en Limba Engleză Hardback – 25 iun 2016

The latest in a series of books from the International Hypoxia Symposia, this volume spans reviews on key topics in hypoxia, and abstracts from poster and oral presentations. The biannual International Hypoxia Symposia are dedicated to hosting the best basic scientific and clinical minds to focus on the integrative and translational biology of hypoxia. Long before ‘translational medicine’ was a catchphrase, the founders of the International Hypoxia Symposia brought together basic scientists, clinicians and physiologists to live, eat, ski, innovate and collaborate in the Canadian Rockies.
This collection of reviews and abstracts is divided into six sections, each covering new and important work relevant to a broad range of researchers interested in how humans adjust to hypoxia, whether on the top of Mt. Everest or in the pulmonary or cardiology clinic at low altitude. The sections include:

Epigenetic Variations in Hypoxia
High Altitude Adaptation
Hypoxia and Sleep
Hypoxia and the Brain
Molecular Oxygen Sensing
Physiological Responses to Hypoxia

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Specificații

ISBN-13: 9781489976765
ISBN-10: 1489976760
Pagini: 245
Ilustrații: XIII, 772 p. 103 illus., 14 illus. in color.
Dimensiuni: 155 x 235 x 48 mm
Greutate: 1.61 kg
Ediția:1st ed. 2016
Editura: Springer Us
Colecția Springer
Seria Advances in Experimental Medicine and Biology

Locul publicării:New York, NY, United States

Public țintă

Research

Cuprins

Epigenetic Mechanisms as anInterface Between the Environment and Genome.- Developmental Origins of HypoxicPulmonary Hypertension and Systemic Vascular Dysfunction: Evidence fromHumans.- Acquired Mitochondrial Abnormalities, Including Epigenetic Inhibitionof Superoxide Dismutase 2, in Pulmonary Hypertension and Cancer: TherapeuticImplications.- Epigenetics in Cardiovascular Regulation.- Why Are High AltitudeNative So Strong at Altitude?: Maximal Oxygen Transport to the Muscle Cell inAltitude Natives.- Novel Insights into Cardiovascular Regulation in Patientswith Chronic Mountain Sickness.- Why Are High Altitude Natives So Strong atHigh Altitude?: Nature vs. Nurture.- Functional Genomic Insights intoRegulatory Mechanisms of High Altitude Adaptation.- Influence of Hypoxia onCerebral Blood Flow Regulation.- Imaging the Respiratory Effects of Opioids in theHuman Brain.- Regional Cerebrovascular Responses to Hypercapnia and Hypoxia.-Implications of Oxygen Homeostasis for Brain Tumors: Biology and Treatment.-Hyperoxia and Functional MRI.- Astrocytes and Brain Hypoxia.- BidirectionalControl of Blood Flow by Astrocytes: A Role for Tissue Oxygen and OtherMetabolic Factors.- Hypoxic Adaptation in the Nervous System: Promise for NovelTherapeutics for Acute and Chronic Neurodegeneration.- Optical Analysis ofHypoxia Inducible Factor (HIF)-1 Complex Assembly: Imaging of Cellular OxygenSensing.- Modulation of the Hypoxic Response.- Central Sleep Apnea at HighAltitude.- Multigenerational Effects of Reading Atmospheric Oxygen Level on theTracheal Dimensions and Diffusing Capacities of Pupal and Adult DrosophilaMelanogaster.- Hypoxia and Its Acid-base Consequences: From Mountains toMalignancy.- Physiological and Clinical Implications of Adrenergic Pathways atHigh Altitude.- Hemoglobin Mass and Aerobic Performance at Moderate Altitude inElite Athletes.- Does the Sympathetic Nervous System Adapt to Chronic AltitudeExposure?.- Integrative Conductance of Oxygen During Exercise at Altitude.-Modeling Variable Phanerozoic Oxygen Effects on Physiology and Evolution.-Caudwell Xtreme Everest: An Overview.- Energy Flux, Lactate Shuttling,Mitochondrial Dynamics, and Hypoxia.- Everest Physiology Pre-2008.

Notă biografică

Dr. Robert Roach is the Director of the Altitude Research Center at the University of Colorado. He specializes in the study of physiological adaptations by humans to high altitude, with a recent emphasis on the genomic responses to allow humans to thrive in hypoxia.

Dr. Peter Wagner is a Distinguished Professor of Medicine and Bioengineering at the University of California, San Diego. His research addresses the theoretical and experimental basis of oxygen transport and its limitations in the lungs and skeletal muscles in health and disease.

Dr. Peter Hackett is a world-renowned high altitude expert and altitude research pioneer. He is a leading authority on altitude illness, high altitude climbing, wilderness medicine, and the effects of altitude on people living and working in the mountains.

Textul de pe ultima copertă

The latest in a series of books from the International Hypoxia Symposia,this volume spans reviews on key topics in hypoxia, and abstracts from posterand oral presentations. The biannual International Hypoxia Symposia arededicated to hosting the best basic scientific and clinical minds to focus onthe integrative and translational biology of hypoxia. Long before‘translational medicine’ was a catchphrase, the founders of the InternationalHypoxia Symposia brought together basic scientists, clinicians andphysiologists to live, eat, ski, innovate and collaborate in the CanadianRockies.
This collection of reviews and abstracts is divided into six sections,each covering new and important work relevant to a broad range of researchersinterested in how humans adjust to hypoxia, whether on the top of Mt. Everestor in the pulmonary or cardiology clinic at low altitude. The sections include:

Epigenetic Variations in Hypoxia
High Altitude Adaptation
Hypoxia and Sleep
Hypoxia and the Brain
Molecular Oxygen Sensing
Physiological Responses to Hypoxia

Dr. Robert Roach is the Director of the Altitude Research Center at theUniversity of Colorado. He specializes in the study of physiologicaladaptations by humans to high altitude, with a recent emphasis on the genomic responsesto allow humans to thrive in hypoxia.
Dr. Peter Wagner is a Distinguished Professorof Medicine and Bioengineering at the University of California, San Diego. Hisresearch addresses the theoretical and experimental basis of oxygen transportand its limitations in the lungs and skeletal muscles in health and disease.
Dr. Peter Hackett is a world-renowned high altitude expert and altituderesearch pioneer. He is a leading authority on altitude illness, high altitudeclimbing, wilderness medicine, and the effects of altitude on people living andworking in the mountains.

Caracteristici

Discusses the latest up-to-date research and discoveries related to hypoxia Spans reviews on key topics in hypoxia Covers findings revealed at the latest International Hypoxia Symposia Includes supplementary material: sn.pub/extras