The two volume set CCIS 775 and 776 constitutes the refereed proceedings of the First International Conference on Computational Intelligence, Communications, and Business Analytics, CICBA 2017, held in Kolkata, India, in March 2017. The 90 revised full papers presented in the two volumes were carefully reviewed and selected from 276 submissions. The papers are organized in topical sections on data science and advanced data analytics; signal processing and communications; microelectronics, sensors, intelligent networks; computational forensics (privacy and security); computational intelligence in bio-computing; computational intelligence in mobile and quantum computing; intelligent data mining and data warehousing; computational intelligence.