At once a comprehensive handbook for the active researcher and a thorough introduction for the advanced student, this reference provides: * Coverage of wide range of applications, including agricultural sciences, animal and biomedi-cal sciences, and industrial and engineering studies * Information on new developments in the design of fractional factorials with non-prime numbers of levels in mixed-level fractional factorials * Detailed information on the construction of plans and the relationships among categories of designs * Thorough discussion of balanced, partially balanced, lattice, cyclic and alpha-designs * Accommodations for how to evaluate the power and efficiency of designs that are not perfectly balanced * Unified and simplified presentation of general forms for estimation and hypothesis testing