This bookhighlights the latest research findings from the 46th International Meeting ofthe Italian Statistical Society (SIS) in Rome, during which both methodologicaland applied statistical research was discussed. This selection of fullypeer-reviewed papers, originally presented at the meeting, addresses a broadrange of topics, including the theory of statistical inference; data mining andmultivariate statistical analysis; survey methodologies; analysis of social,demographic and health data; and economic statistics and econometrics.