Computerized sequence analysis is an integral part of biotechnological research, yet many biologists have received no formal training in this important technology. Sequence Analysis Primer offers the necessary background to enter this exploding field and helps more seasoned researchers to fine-tune their approach. Compatible with most sequence analysis programs, the primer covers basic data manipulation, and offers valuable advice for overcoming common problems. A detailed example giving steps for characterizing a new gene sequence provides users with "hands-on" experience when combined with their current software.