How do the great discoverers of science really work? Biographers, psychologists, and philosophers have written much on the phenomenon of scientific creativity. This collection of essays takes you into the minds of some of the world's greatest scientists. You can read in their own words how they worked, thought, and discovered crucial insights. Hermann von Helmholtz, Hideki Yukawa, Ernst Mach, J.B.S. Haldane, Steven Weinberg, Peter Doherty, C.V. Raman, Sylvester James Gates, and many more deliver witty, irreverent, thoughtful, and profound advice to scientists of all kinds and abilities. Whether you are a science hobbyist, an undergraduate doing your first lab work, a postdoc, or a seasoned professional, these essays will help point you in the direction of insight and discovery.