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Proteins: Concepts in Biochemistry

Autor Paulo Almeida
en Limba Engleză Paperback – 2 noi 2025
Proteins: Concepts in Biochemistry teaches the biochemical concepts underlying protein structure, evolution, stability, folding, and enzyme kinetics, and explains how interactions in macromolecular structures determine protein function. Intended for a one-semester course in biochemistry or biophysical chemistry with a focus on proteins, this textbook emphasizes the logic underlying biophysical chemical principles.
Problems throughout the book encourage statistical and quantitative thinking. The text is ideal for senior undergraduates, first-year graduate students, and practitioners in chemistry, biochemistry, biology and biophysics.
Key Features:
  • Focuses on the interdisciplinary aspect of protein biophysical chemistry, offering a quantitative description of proteins that integrates concepts from organic chemistry, physical chemistry and biology
  • Written in consideration of the requirements for an ACS-certified BS degree in chemistry, the text meets the recommendations of the American Chemical Society, National Research Council, and National Science Foundation to feature more biochemistry and quantitative study in the life sciences
  • Each chapter ends with problem sets, with a complete solutions manual available to instructors, and key references for further reading
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Specificații

ISBN-13: 9781032518404
ISBN-10: 1032518405
Pagini: 410
Ilustrații: 712
Dimensiuni: 210 x 280 x 22 mm
Greutate: 0.76 kg
Ediția:2. Auflage
Editura: CRC Press
Colecția Garland Science

Public țintă

Postgraduate and Undergraduate

Cuprins

1.Statistical Thermodynamics of Biological Molecules
2.Protein Structure
3.Evolution of Protein Sequence and Structure
4.Protein Stability
5.Protein Folding
6.Binding, Allostery, and Cooperativity
7.Enzyme Kinetics
Appendix A. Calculation of the excess heat capacity curve of protein thermal denaturation
Appendix B. Calculation of the average helicity from the partition function
Appendix C. Solution of rate equations for two-state system
Appendix D.Steady-State Rates of Complex Enzyme Reactions  

Notă biografică

Paulo Almeida is a Professor in the Department of Chemistry and Biochemistry at the University of North Carolina Wilmington. Prior to his academic appointment at UNCW, he was an Assistant Professor of Chemistry at the University of Coimbra and at the University of Algarve, Portugal. His research seeks to understand the mechanism of antimicrobial, cytolytic peptides, and cell-penetrating peptides, as well as study domain formation in lipid membranes in terms of the molecular interactions between lipids, and how they are influenced by proteins and peptides bound or incorporated into the membrane. Almeida is a member of the Editorial Board of Biophysical Journal, as well as a member of the Biophysical Society and American Chemical Society. Almeida has written several book chapters in addition to being an active reviewer for professional journals and author of numerous papers.

Descriere

Proteins: Concepts in Biochemistry teaches the biochemical concepts underlying protein structure, evolution, stability, folding, and enzyme kinetics, and explains how interactions in macromolecular structures determine protein function.