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Progress in Medicinal Chemistry de David R. Witty

Progress in Medicinal Chemistry: Progress in Medicinal Chemistry, cartea 57

David R. Witty, Brian Cox
en Limba Engleză Hardback – 10 apr 2018
Progress in Medicinal Chemistry, Volume 57, provides a review of eclectic developments in medicinal chemistry, with this volume including chapters on the CaSR field, CFTR modulators in cystic fibrosis, macrocycles, VMAT2 inhibitors, and Big Data in Drug Discovery.


  • Provides extended, timely reviews of topics in medicinal chemistry
  • Contains targets and technologies relevant to the discovery of tomorrow’s drugs
  • Presents analyses of successful drug discovery programs
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Specificații

ISBN-13: 9780128152133
ISBN-10: 0128152133
Pagini: 366
Dimensiuni: 152 x 229 mm
Greutate: 0.66 kg
Editura: ELSEVIER SCIENCE
Seria Progress in Medicinal Chemistry

Public țintă

Everyone interested in the strategy and practice of the preclinical phases of the creation of new medicines. Those wishing to understand the drivers of drug design or expand their knowledge of therapeutic target classes

Cuprins

1. Discovery and Development of Calcimimetic and Calcilytic Compounds
Edward F. Nemeth, Bradford C. Van Wagenen and Manuel F. Balandrin
2. VMAT2 Inhibitors and the Path to Ingrezza (Valbenazine)
Nicole D. Harriott, John P. Williams, Evan B. Smith, Haig P. Bozigian and Dimitri E. Grigoriadis
3. Current Trends in Macrocyclic Drug Discovery and Beyond-Ro5
Sulejman Alihodzic, Mirjana Bukvic, Ivaylo J. Elenkov, Antun Hutinec, Sanja Koštrun, Dijana Pesic, Gordon Saxty, Linda Tomaškovic and Dinko Ziher
4. Recent Progress in the Discovery and Development of Small-Molecule Modulators of CFTR
Phil R. Kym, Xueqing Wang, Mathieu Pizzonero and Steven E. Van der Plas
5. Big Data in Drug Discovery
Nathan Brown, Jean Cambruzzi, Peter J. Cox, Mark Davies, James Dunbar, Dean Plumbley, Matthew A. Sellwood, Aaron Sim, Bryn I. Williams-Jones, Magdalena Zwierzyna and David W. Sheppard