Progress in Medicinal Chemistry, Volume 65 brings together state-of-the-art reviews and critical insights from leading scientists in the field. Each volume surveys the latest advances in drug discovery and development, with a focus on practical strategies, novel modalities, and real-world case studies. From target identification and structure-based design to optimization of pharmacokinetic properties, safety assessment, and translational science, these volumes provide a comprehensive, up-to-date overview for researchers, graduate students, and professionals working in medicinal chemistry, pharmacology, and related life sciences.

Chapters in this new release cover Molecular Glues and Tactics in Hit Finding through to Lead Generation in Drug Discovery – current position and future directions.

• Provides in-depth surveys of cutting-edge topics in medicinal chemistry
• Summaries recent discoveries, trends, and emerging therapeutic areas
• Delves into structure–activity relationships (SAR) and optimization principles