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Perinatal Stem Cells de Anthony Atala

Perinatal Stem Cells

Editat de Anthony Atala, Sean V. Murphy
en Limba Engleză Paperback – 22 sep 2016

Bazându-ne pe datele furnizate de Springer și pe expertiza academică a editorilor Anthony Atala și Sean V. Murphy, recomandăm acest volum ca fiind o resursă definitorie pentru medicina regenerativă contemporană. Publicat în ediția din 2014, Perinatal Stem Cells oferă o perspectivă tehnică riguroasă asupra biologiei și potențialului terapeutic al celulelor stem de origine perinatală, un domeniu aflat la granița dintre biologia dezvoltării și aplicația clinică.

Structura cărții este organizată progresiv în patru secțiuni majore, facilitând o înțelegere aprofundată a surselor de celule stem (lichid amniotic, placentă, membrane placentare și cordon umbilical). Găsim în cele 32 de capitole nu doar baze teoretice, ci și analize detaliate ale protocoalelor de izolare și caracterizare, esențiale pentru cercetători. Un aspect distinctiv al acestui volum este accentul pus pe „traducerea clinică” — procesul complex de a transforma descoperirile de laborator în tratamente viabile pentru afecțiuni precum regenerarea hematopoietică sau bolile inflamatorii.

Cititorii familiarizați cu Perinatal Tissue-Derived Stem Cells de Babak Arjmand vor aprecia în acest volum rigoarea cu care sunt tratate procesele de producție și stocare (banking), oferind un cadru mai aplicat pentru standardele industriale actuale. În contextul operei sale vaste, Anthony Atala integrează aici temele explorate în Essentials of Stem Cell Biology, dar cu o focalizare mult mai specifică pe sursele perinatale, completând astfel viziunea sa asupra regenerării țesuturilor începută în lucrări precum Handbook of Tissue Engineering Scaffolds. Ritmul expunerii este unul academic, dens în date experimentale, reflectând rigoarea unei cercetări de nivel înalt.

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Specificații

ISBN-13: 9781493946242
ISBN-10: 1493946242
Pagini: 400
Ilustrații: XXIII, 373 p. 101 illus., 87 illus. in color.
Dimensiuni: 210 x 279 x 21 mm
Greutate: 1.09 kg
Ediția:Softcover reprint of the original 1st ed. 2014
Editura: Springer
Locul publicării:New York, NY, United States

De ce să citești această carte

Recomandăm această carte cercetătorilor și clinicienilor care doresc să stăpânească biologia celulelor stem perinatale. Este un ghid esențial pentru înțelegerea tranziției de la pre-clinic la clinic, oferind soluții concrete pentru regenerarea cardiacă, pulmonară și osoasă. Cititorul câștigă acces la expertiza Dr. Anthony Atala, un pionier global în ingineria tisulară, obținând o imagine clară asupra viitorului terapiilor celulare și al proceselor de banking.

Despre autor

Dr. Anthony Atala este bioinginer, urolog și chirurg pediatru de renume mondial, ocupând funcția de director fondator al Wake Forest Institute for Regenerative Medicine. Este recunoscut la nivel global pentru crearea primelor bioprimante 3D de țesuturi (ITOP) și pentru dezvoltarea primului organ crescut în laborator — o vezică urinară — implantat cu succes unui pacient uman. Cu peste 800 de articole publicate și 250 de brevete, Dr. Atala a editat 25 de cărți fundamentale în domeniu, munca sa fiind dedicată refacerii țesuturilor afectate prin utilizarea propriilor celule sănătoase ale corpului.

Descriere scurtă

This comprehensive volume is one of the first books to offer the reader detailed insight into sources of perinatal stem cells, their biology,  and their potential for disease treatment. It examines the research and therapeutic applications of perinatal stem cells including the treatment of renal disease, hematopoietic regeneration, cardiac disease, inflammatory disease, bone regeneration, pulmonary disease, and the treatment of spinal cord injury. Further, the book discusses current progress in the manufacturing, banking and clinical translation of perinatal stem cells. Through this book, readers will gain a thorough understanding of the current pre-clinical and clinical applications of perinatal stem cells as well as the efforts to support the transition of perinatal stem cell therapies from laboratories to clinics.
Perinatal Stem Cells contains thirty-two chapters written by internationally recognized leaders in stem cell research. It is organized into four sections covering amniotic fluid stem cells, placental and placental membrane stem cells, umbilical cord stem cells, and clinical translation. This cohesive structure provides an effective framework for detailed insight into this new frontier. Edited by Dr. Anthony Atala, one of the foremost experts in the field, and his co-editor Dr. Sean V. Murphy, this volume is a definitive work for stem cell research and its future implications. It is a key resource for all stem cell researchers, clinicians, and government and industry staff working in this dynamic and exciting field.

Cuprins

1 Amniotic Fluid Stem Cells for Cardiac Regeneration.- 2 Amniotic Fluid Stem Cells for Wound Healing .- 3 Treatment of Necrotising Enterocolitis (NEC) with Amniotic Fluid Stem Cells.- 4 Therapeutic Application of Amniotic Fluid Stem Cells for Graft-versus-Host Disease.- 5 Amniotic Fluid Stem Cell Features Supporting their Putative Role in Fetal Cell Microchimerism.- 6 Amniotic Fluid Stem Cell Therapy for Lung Disease.- 7 Direct Reprogramming of Amniotic Cells into Endothelial Cells.- 8 Amniotic Fluid Stem Cells for the Treatment of Articular Cartilage Defects.- 9 Amniotic Fluid-Derived Cells: An Autologous Cell Source for Cardiovascular Tissue Engineering.- 10 Amniotic Fluid Stem Cells for Bone Tissue Engineering.- 11 Amniotic Fluid Stem Cells for the Repair of Prenatal and Perinatal Defects.- 12 Stimulation of Therapeutic Angiogenesis Using Amniotic Fluid Stem Cells.- 13 Placental Stem/Progenitor Cells: Isolation and Characterization.- 14 Treatment of Liver Disease using Placental Stem Cells: Feasibility of Placental Stem Cells in Liver Diseases: Potential Implication of New Cell Therapy-Based Strategies for Hepatic Diseases.- 15 The Human Term Placenta as a Source of Transplantable Hematopoietic Stem Cells.- 16 Placental Stem Cells for Cartilage Tissue Engineering.- 17 Mesenchymal Stem Cells from Human Amniotic Membrane.- 18 Bladder Reconstruction Using Amniotic Mesenchymal Stem Cells.- 19 Amnion Epithelial Cells for Lung Diseases.- 20 Potential Efficacy of Amnion Epithelial Cells to Treat Post-Stroke Inflammation.- 21 The Potential of Human Amnion Epithelial Cells as an Immunomodulatory and Neuroregenerative Treatment for Multiple Sclerosis.- 22 Human Amniotic Epithelial Cells Transplantation for Contusive Spinal Cord Injury Repair.- 23 Therapeutic Potential of Amnion Epithelial Cells for Diabetes.- 24 Collection, Processing & Banking of Umbilical Cord Blood.- 25 Umbilical Cord Blood Cells in the Repair of Central Nervous System Diseases.- 26 Umbilical Cord Blood for Cardiovascular Cell Therapy.- 27 Bone Regeneration using Wharton's Jelly Mesenchymal Stem Cells.- 28 Wharton's Jelly Mesenchymal Stem Cells for the Treatment of Type 1 Diabetes.- 29 Umbilical Cord Blood-Derived Endothelial Progenitor Cells for Cardiovascular Tissue Engineering.- 30 Manufacturing Perinatal Stem Cells for Clinical Applications.- 31 Towards Clinical Applications of Umbilical Cord Derived Mesenchymal Stem Cells.- 32 Recent Patents on Perinatal Stem Cells.

Recenzii

From the book reviews:
“This book would be an excellent resource for graduate students in the field of perinatal stem cells. Other researchers in the stem cell field (postdocs, PIs) may also benefit. … This book offers a comprehensive overview and review of the use of perinatal stem cells in both the clinical and preclinical settings. It is essential for students and postdocs studying perinatal stem cells.” (Ellen Mary Andrews, Doody’s Book Reviews, January, 2015)

Notă biografică

Dr. Anthony Atala is widely recognized as a true groundbreaker in stem cell research and regenerative medicine. He led the team that grew the first lab-grown organ to be implanted into a human. Aside from being involved in many of the field’s top journals, he has devoted the last several decades of his career to the development of sustainable organs grown from a patient’s own stem cells – technology that has the potential to solve the problem of patients dying while waiting for organs as well as the common organ transplant complication of rejection. Dr. Atala received a bachelor’s degree in psychology from the University of Miami and his medical degree from the University of Louisville, where he completed his residency in urology. While a Fellow at Harvard Medical School, he trained with renowned pediatric urologic surgeons and eventually became Director of the Laboratory for Tissue Engineering and Cellular Therapeutics at Children's Hospital Boston, where his work involved the growing of human tissue and organs to replace those damaged through disease or defect. After that, Dr. Atala moved to Wake Forest, and it was there that he and his team developed the lab-grown bladder that was implanted in a human. A prolific author and editor of journal articles and books, Dr. Atala is the recipient of multiple awards and patents, presented an ovation-receiving TED lecture, and has been featured on 60 Minutes. His accomplishments also include being ranked as the 56th most influential person of the year in a Time Magazine poll and being ranked by Esquire Magazine as one of the 75 most influential persons of the 21st century.
Dr. Sean V. Murphy received his Ph.D. from Monash University, Melbourne, Australia and is currently a Research Fellow at the Wake Forest Institute for Regenerative Medicine in North Carolina, USA. His research focuses on the clinical application of perinatal cells and tissues for the treatment of injury and disease. Dr. Murphyhas received numerous awards and fellowships, most notably an American Lung Association Senior Research Training Fellowship, and an American Australian Association Sir Keith Murdoch Fellowship. Dr. Murphy is Director/Secretary and Founder of the International Perinatal Stem Cell Society, Chair of the Scientific & Professional Development Committee for the Tissue Engineering and Regenerative Medicine International Society (TERMIS) and serves on the editorial board of multiple international journals.

Caracteristici

Explores current clinical and pre-clinical application of stem cells derived from perinatal sources Offers detailed insight into sources of perinatal stem cells and their potential for disease treatment Discusses progress in the manufacturing, banking and clinical translation of perinatal stem cells Includes supplementary material: sn.pub/extras