The Mediterranean is a diverse and volatile region, especially in its post—Cold War state, and it is entering a new phase of uncertainty. Twenty-two sovereign states surround this body of water: six are part of the Western alliance system, three have engaged in or supported terrorism, and others face serious internal tensions arising from territorial claims and ethnic strife. This special issue of Mediterranean Quarterly brings together scholars and policy makers representing a wide variety of interests and ideas to discuss this unique region and to explore its prospects for peace and stability.The potential role of NATO is controversial but crucial to the future of the Mediterranean. Some contributors suggest that the southward expansion of NATO could be an important first step toward stability, while others argue that the Mediterranean should be treated as an integrated geostrategic region, with a central place in Western security considerations.Highlighting this issue is a foreword by former U.S. Secretary of State George P. Schultz, and a piece focusing on NATO in the Mediterranean by Javier Solana, the Secretary General of NATO. Other essays discuss the comparative experience of UNPROFOR and IFOR in the former Yugoslavia; the role of Italy in the future of the Mediterranean; the economic challenges facing the Middle East; and the role of Israel and its relationship to its neighbours. Mediterranean Security at the Crossroads is one of the first in-depth looks at this region from a strictly post—Cold War perspective.