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Endogenous ADP-Ribosylation de Friedrich Koch-Nolte

Endogenous ADP-Ribosylation: Current Topics in Microbiology and Immunology, cartea 384

Editat de Friedrich Koch-Nolte
en Limba Engleză Paperback – 23 aug 2016
This volume gathers the latest exciting findings on ADP-ribosylation from renowned experts in the field. It includes ten chapters, organized into the following three thematic sections:
·   Evolution and detection of endogenous ADP-ribosylation
·   ADP-ribosylation by the ARTC family of ADP-ribosyltransferases (R-S-E ARTs)
·   ADP-ribosylation by the ARTD family of ADP-ribosyltransferases (H-Y-E ARTs)
The book will provide readers a better understanding of ADP-ribosylating toxins and their endogenous relatives. This provides a basis for developing novel toxin-neutralizing drugs and drugs targeting endogenous ADP-ribosyltransferase relatives.
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Specificații

ISBN-13: 9783319345970
ISBN-10: 3319345974
Pagini: 221
Ilustrații: VIII, 213 p.
Dimensiuni: 155 x 235 x 12 mm
Greutate: 0.32 kg
Ediția:Softcover reprint of the original 1st ed. 2015
Editura: Springer International Publishing
Colecția Springer
Seria Current Topics in Microbiology and Immunology

Locul publicării:Cham, Switzerland

Cuprins

The natural history of ADP-ribosyltransferases and the ADP ribosylation system.- Identification and Analysis of ADP-ribosylated Proteins.- Photorhabdus luminescens toxins TccC3 and TccC5: Insecticidal ADP-ribosyltransferases that modify threonine and glutamine.- Reaction mechanism of mono-ADP-ribosyltransferase based on structures of the complex of enzyme and substrate protein.- Regulation of nitrogenase by reversible mono-ADP-ribosylation.- ADP-ribosylation of P2X7: a matter of life and death for regulatory T cells and natural killer T cells.- Pierisins and CARP-1: ADP-ribosylation of DNA by ARTCs in butterflies and shellfish.- Comparative structural analysis of the putative mono-ADP-ribosyltransferases of the ARTD/PARP family.- Function and regulation of the mono-ADP-ribosyltransferase ARTD10.- Regulation of nucleocytoplasmic transport by ADP-ribosylation: the emerging role of karyopherin-β1 mono-ADP-ribosylation by ARTD15.

Notă biografică

Friedrich Koch-Nolte is a professor at University Hospital Hamburg-Eppendorf, Institute for Immunology, Hamburg, Germany

Textul de pe ultima copertă

This volume gathers the latest exciting findings on ADP-ribosylation from renowned experts in the field. It includes ten chapters, organized into the following three thematic sections:
 ·   Evolution and detection of endogenous ADP-ribosylation
 ·   ADP-ribosylation by the ARTC family of ADP-ribosyltransferases (R-S-E ARTs)
  ·   ADP-ribosylation by the ARTD family of ADP-ribosyltransferases (H-Y-E ARTs)
The book will provide readers a better understanding of ADP-ribosylating toxins and their endogenous relatives. This provides a basis for developing novel toxin-neutralizing drugs and drugs targeting endogenous ADP-ribosyltransferase relatives.

Caracteristici

Broadens your understanding of endogenous mono-ADP-ribosylation reactions Brings together exciting recent findings on ADP-ribosylation Written by leading experts in the field Includes supplementary material: sn.pub/extras