This research discuses the mechanism of developing E-commerce application with enhance security level through combined access control methods with cryptography function (message digest five) , the main purpose of developing multidisciplinary security system expected is to increase the level of confidentiality percentage for the final E-commerce application. Security is concerned with the privacy of the database tables whether the data is saved against eavesdropping, or theft of information from server, and also theft of data from client. Hence the depth of discussing the components of E-commerce security is based on smart card securityissues. The problem of protecting the application through the internet environment against threats that comes from hackers and confidentiality has also been discussed.