Bone Metastasis and Molecular Mechanisms de Gurmit Singh

Bone Metastasis and Molecular Mechanisms: Pathophysiology: Cancer Metastasis - Biology and Treatment, cartea 6

Gurmit Singh

William Orr

Patients with advanced breast or prostate cancers usually develop bone metastases. The principal complications resulting from metastatic bone disease are pain, spinal cord compression, pathologic fractures and bone marrow suppression. Improving the management of bone metastases is crucial to quality of life for patients with breast and prostate cancer.
Advances in understanding of the molecular mechanisms underlying the pathophysiology of bone metastasis are driving the development of new therapeutic strategies.

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Paperback (1)	1053^.35 lei 43-57 zile
SPRINGER NETHERLANDS – 6 dec 2010	1053^.35 lei 43-57 zile
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SPRINGER NETHERLANDS – 31 mar 2004	1058^.46 lei 43-57 zile

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Express

Paperback (1)

1053^.35 lei 43-57 zile

SPRINGER NETHERLANDS – 6 dec 2010

1053^.35 lei 43-57 zile

Hardback (1)

1058^.46 lei 43-57 zile

SPRINGER NETHERLANDS – 31 mar 2004

1058^.46 lei 43-57 zile

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Specificații

ISBN-13: 9789048165636
ISBN-10: 9048165636
Pagini: 328
Ilustrații: XVI, 308 p.
Dimensiuni: 155 x 235 x 17 mm
Greutate: 0.46 kg
Ediția:Softcover reprint of hardcover 1st ed. 2004
Editura: SPRINGER NETHERLANDS
Colecția Springer
Seria Cancer Metastasis - Biology and Treatment

Locul publicării:Dordrecht, Netherlands

Cuprins

1 Models of Breast Cancer Metastasis to Bone: Characterization of a Clinically Relevant Model.- 2 Quantitation of Bone Metastasis in Experimental Systems.- 3 Comparative Morphometric Study on Bone Remodeling in Human Specimens and in Experimental Models of Metastatic Bone Disease.- 4 Clinical Modalities for the Diagnosis, Characterization and Detection of Bone Metastases.- 5 Metastasis in the Bone Marrow Microenviroment.- 6 The Role of Tumor-Associated Macrophages in Metastasis-Associated Osteolysis.- 7 The Malignant Hierarchy in Multiple Myeloma: Relationships between Malignant Cells and Bone Disease.- 8 Angiogenesis and Lymphangiogenesis in Metastatic Bone Disease: A Matter of Networking.- 9 Prostate Cancer: Models for Developing Novel Therapeutic Approaches.- 10 Potential Therapeutic Targets for Bone Metastasis.- 11 OPG, RANK and RANKL in Bone Metastasis and Cancer-Associated Osteolysis.- 12 Role of Matrix Metalloproteinases in Bone Metastasis from Human Breast and Prostate Cancer.- 13 The Role of Bisphosphonates in Bone Metastasis.