This book reports on advanced theories and methods in three related fields of research: applied physics, system science and computers. It is organized in two main parts, the first of which covers applied physics topics, including lasers and accelerators; condensed matter, soft matter and materials science; nanoscience and quantum engineering; atomic, molecular, optical and plasma physics; as well as nuclear and high-energy particle physics. It also addresses astrophysics, gravitation, earth and environmental science, as well as medical and biological physics. The second part focuses on advances in system science and computers, exploring automatic circuit control, power systems, computer communication, fluid mechanics, simulation and modeling, software engineering, data structures and applications of artificial intelligence among other areas. Offering a collection of contributions presented at the 1st International Conference on Applied Physics, System Science and Computers (APSAC 2016), the book bridges the gap between applied physics and electrical engineering. It not only to presents new methods, but also promotes collaborations between different communities working on related topics at the interface between physics and engineering, with a special focus on communication, data modeling and visualization, quantum information, applied mechanics as well as bio and geophysics.