When high school teacher Chase McCarthy begins serving as a mentor to her beautiful colleague, she has no idea that the younger woman will steal her husband and have his child-the child that she cannot have. But life gets worse when Chase moves to southern Colorado and discovers that she has breast cancer. After a year of chemotherapy and an intense battle for her life, Chase meets a female white dog with yellow eyes at an animal shelter. Chase hopes to help the dog, which she names Snow, but instead finds out that she's the one in need of rescuing.
Chase soon finds out that Snow is probably part wolf, but that does not deter her from loving the animal. As Chase and Snow become better acquainted and learn each other's ways, the wolf-dog also gets to know Nathaniel Black, a teacher at a community college. Snow becomes enamored with the handsome teacher, and soon, so does her owner.
"When the Wolf Howls" is the inspiring story of a woman scorned and the dog who teaches her the true meaning of love.