Voigt′s Pharmaceutical Technology

Contributors vii Foreword ix Acknowledgements xiii List of Abbreviations xv Index of Pharmacopeia Boxes xix Part I Dosage Forms 1 Drug Formulations as Application System-Science and Legal Provisions 3 Part II General and Technological Principles and Unit Operations 2 Unit Operations 13 3 Physical and Physicochemical Principles of Drug Formulation 39 4 Sterilization of Drug Formulations: Procedures to Reduce Microbial Count 133 5 Excipients for Drug Formulation 161 6 Basic Principles of Probability and Statistics 241 7 Basic Principles in Biopharmaceutics 279 Part III Solid Dosage Forms 8 Powders and Granules 319 9 Tablets 345 10 Coated Oral Dosage Forms 377 11 Capsules 395 12 Peroral Modified Release (MR) Formulations 409 13 Rectal Preparations 429 14 Vaginal Dosage Forms and Dosage Forms to be Introduced in Body Cavities 447 Part IV Semi-Solid Dosage Forms 15 Semi-Solid Preparations for Cutaneous Application 453 16 Patches/Plasters 517 Part V Liquid Dosage Forms 17 Solutions 529 18 Emulsions 537 19 Suspensions 557 20 Micro- and Nanodispersed Systems 569 21 Parenteral Formulations 581 22 Ophthalmic Preparations 623 Part VI Gaseous Dosage Forms 23 Inhalation Dosage Forms 637 Part VII General Aspects of Dosage Forms 24 Herbal Drug Preparations (Extracts, Tinctures, and Aqueous Preparations) 659 25 Stability and Stabilization 681 26 Incompatibilities 707 27 Packaging Materials and Technology 721 28 Recent and Future Developments in Pharmaceutical Technology 749 Appendix A Selected Dosage Forms (Compared between Ph. Eur., USP, and JP) 757 Index 817