From a wealthy cul-de-sac in Hillsborough, California to a dusty village in Central Mexico, Tio Jorge gives us an emotional portrait of a young woman who cannot move forward until she silences the ghosts of her tragic childhood. On her graduation day from Stanford University, she thinks she sees in the crowd the man accused of her mother's death sixteen years earlier, but he flees before she can speak to him. Believing he is the key to unlock the mystery of her father who abandoned her, she sets out to track him down, and in the process discovers the Mexican side of her family. Heartened by the love and warmth of her Mexican relatives, she has the courage to confront her mother's family and seek justice for the man who had been her father's secret lover.