In 1860 Prussia, Otto is busy raising his daughter and worrying about his wife, who is under the control of drugs. The common drugs in 1860 were opium and alcohol, along with new discoveries such as cocaine and morphium, and the tinctures and potions of the people. Otto's doctor sets out a way Otto can get Hildegard off the drugs, but before Otto can do anything, some awful things happen. Young girls are attacked on his estate, someone is stealing, and a man is murdered in bed. Who is doing the crimes? And why?