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The Vitreous: Structure, Function, and Pathobiology

Autor J. Sebag Prefață de C.L. Schepens
en Limba Engleză Paperback – 8 noi 2011
The vitreous body long has been the most mysterious of all ocular structures, owing perhaps to its seeming simplicity. There have been few concerted, sustained efforts to unravel the mysteries of how the vitreous is composed and what role it plays in normal physiology. Over the years, however, many studies have produced independent findings concerning vitreous biochemistry, structure, and physiology. The Vitreous organizes these findings into a well-constructed compendium that not only addresses the most current scientific knowledge, but also reviews historical perspec­ tives in a manner that lends richness to the scope of the book. The first few chapters present an exhaustive, yet readable, review of the body of scientific data that have come from laboratories and researchers throughout the world. Extensive bibliographies direct interested readers further into specific aspects of the basic science of the vitreous. Chapter II: "Embryology" and Chapter IV: "Structure" present a novel organizational approach to assembling and presenting data in an integrated manner. Chapter V: "Functions" and Chapter VI: "Development and Aging" introduce fresh perspectives on the importance of the vitreous as some­ thing more than a vestigial space filler within the eye.
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Specificații

ISBN-13: 9781461389101
ISBN-10: 1461389100
Pagini: 192
Ilustrații: XIII, 173 p.
Dimensiuni: 178 x 254 x 10 mm
Greutate: 0.36 kg
Ediția:Softcover reprint of the original 1st ed. 1989
Editura: Springer
Colecția Springer
Locul publicării:New York, NY, United States

Public țintă

Research

Cuprins

I Introduction.- A. General Background.- B. Historical Perspective.- References.- II Embryology of the Vitreous.- A. Structural Development.- B. Cellular Development.- C. Molecular Development.- References.- III Biochemistry.- A. Collagen.- B. Hyaluronic Acid (HA).- C. Collagen-HA Interaction.- D. Noncollagenous Proteins.- E. Glycoproteins.- F. Low-Molecular-Weight Substances.- G. Miscellaneous Compounds.- H. Species Variations.- References.- IV Structure of the Vitreous.- A. Organization and Distribution of Molecular Components.- B. Vitreous Body.- C. Vitreous Base.- D. Vitreous Cortex.- E. Basal Laminae and Vitreoretinal Interface.- F. Zonules.- References.- V Functions of the Vitreous.- A. Developmental.- B. Optical.- C. Mechanical.- D. Physiology and Metabolism.- References.- VI Development and Aging of the Vitreous.- A. Development to the Adult.- B. Aging.- C. Posterior Vitreous Detachment.- References.- VII Pathobiology of the Vitreous.- A. Developmental and Inherited Disorders.- B. Connective-Tissue Disorders.- C. Diabetes Mellitus.- D. Cell Invasion.- E. Vascular Invasion and Effects of Vitreous Hemorrhage.- F. Vitreoretinal Traction.- G. Miscellaneous Conditions of the Vitreous.- H. Effects of Surgical Intervention.- References.- Color Plates.

Recenzii

“A striking feature of this textbook is the stunningly vivid color illustrations that have remarkable resolution, in spite of considerably large size. Graphs and tables are featured in both grayscale and color, adding significantly to the ease of comprehension when reading this book. … this book is not only useful to skilled clinicians and expert scientists, but also students, as the book has no competition anywhere in the world.” (Taiji Sakamoto, Graefe's Archive for Clinical and Experimental Ophthalmology, Vol. 257, 2019)
 

Notă biografică

Editor:
J. Sebag, MD, FACS, FRCOphth, FARVO
VMR Institute for Vitreous Macula Retina
7677 Center Avenue, suite 400
Huntington Beach, CA 92647


Textul de pe ultima copertă

The vitreous body long has been the most mysterious of all ocular structures, owing perhaps to its seeming simplicity. There have been few concerted, sustained efforts to unravel the mysteries of how vitreous is composed and what role it plays in normal physiology as well as pathology. Over the years, however, many studies have produced important findings concerning vitreous biochemistry, structure, physiology, and pathobiology. Published on the 25th anniversary of Sebag's first book on Vitreous, this second installment is nearly five times longer than its predecessor, reflecting how much has been learned in the past quarter century. This well-constructed compendium not only addresses the most current scientific knowledge, but also reviews clinical perspec­tives in a manner that lends richness to the scope of the book.
 Written by 90 authors, this book has 56 chapters organized into 7 sections: Biochemistry; Anatomy, Development, and Aging; Pathology/Pathobiology; Physiology and Phamacotherapy; Posterior Vitreo-Retinal Surgery; Peripheral Vitreo-Retinal Surgery; and Pharmacologic Vitreolysis. With a foreword by Coleman & Lincoff and an introduction by Wallace Foulds, Sebag's latest tome on vitreous is destined to be the authoritative text for years to come.

Caracteristici

Presents a comprehensive overview of the biochemical composition, molecular organization, morphologic structure, physiology and metabolism of the vitreous body of the eye Highlights both the advances in vitreo-retinal surgery of today with text and video of surgery, along with the non-surgical approaches of the future, namely pharmacologic vitreolysis Clinicians can use this text as a basic science reference manual and researchers will obtain a better understanding of the problems that confront clinicians, helping direct their research to the areas relevant to clinical problems that need development