This new paperback edition makes available John Harley Warner's highly influential, revisionary history of nineteenth-century American medicine. Deftly integrating social and intellectual perspectives, Warner explores a crucial shift in medical history, when physicians no longer took for granted such established therapies as bloodletting, alcohol, and opium and began to question the sources and character of their therapeutic knowledge. He examines what this transformation meant in terms of patient care and assesses the impact of clinical research, educational reform, unorthodox medical movements, newly imported European method, and the products of laboratory science on medical ideology and action. Originally published in 1997. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.