Lou, a young Black woman, wakes up in an alley in 1930s Los Angeles with no memory of how she got there or where she's from. Taken in by a caring foster family, Lou dedicates herself to her education while trying to put her mysterious origins behind her. When she befriends a firefighter at a downtown boxing gym, Lou is shocked to realise that though she has no memory of meeting him, she's been drawing his face for years. Increasingly certain that their paths previously crossed - and beset by unexplainable flashes from different eras haunting her dreams - Lou begins to believe she may be an immortal sent here for a very important reason, one that only others like her can explain. Setting out to investigate the mystery of her existence, Lou must make sense of the jumble of lifetimes calling to her, just as new forces threaten the existence of those around her.