Twenty-year-old Sibel thought she had concrete plans for the summer. She would care for her grandmother in Istanbul, visit her father's grave, and study for the MCAT. Instead, she finds herself watching Turkish soap operas and self-diagnosing her own possible chronic illness with the four humours theory of ancient medicine. Also on Sibel's mind: her blond American boyfriend who accompanies her to Turkey; her energetic but distraught younger sister; and her devoted grandmother, who, Sibel comes to learn, carries a harrowing secret.