Big science and advanced technology are known to cross-fertilize each other. This book emphasizes the interplay between particle physics and technology having led to breakthroughs in research and technology throughout the 60-year of CERN. The context, which led to outstanding technological innovations at CERN, often obtained by individuals or by small teams, and its impact on research, is illustrated with selected highlights, covering advances in accelerator and experimental technologies. The book presents the framework and conditions prevailing at CERN, enabling many spectacular technological advances, propelling this European organization into the league of leading research laboratories in the world.While the book provides information of interest to more expert readers, it specifically aims at the technically interested public. References are given for readers who wish to further explore a topic.