Supercritical fluid chromatography (SFC) is a rapidly developing laboratory technique for the separation and identification of compounds in mixtures. Recent, significant improvements in instrumentation have rekindled interest in SFC and have enhanced its standing in the scientific community. Many scientists are familiar with column liquid chromatography and its potential beyond traditional liquid chromatography, yet many of its capabilities remain underappreciated. Supercritical Fluid Chromatography and Extraction explores contemporary supercritical fluid chromatography and extraction and how it should be implemented in laboratory science for analysis, isolation, and production.

New to This Edition
This new edition details recent advances and applications of supercritical fluids in sample prep, instrumental analysis, and process-scale, including SFE, making it a comprehensive resource for both techniques. Further enhancements to this edition include:

• Expanded section on SFC theory to include gradient elution
• A new chapter on general detectors for SFC
• Enhanced method development coverage, with focus on gradient elution practices
• Includes multidimensional SFC, SFC × SFC, and LC-SFC
• Features comprehensive information on accelerated solvents, comparing solvent and extraction techniques.
• Highlights environmental monitoring and analysis applications of SFE.

Widely used in the food industry for decades, SFE is now expanding into new fields. Supercritical Fluid Chromatography and Extraction, Second Edition serves as a valuable resource for chemical engineers, chemists, researchers, students, and academics working with supercritical fluids at preparative and process scales. It’s also an ideal introduction for newcomers to SFC and SFE.

• Covers method development for SFC and SFE across instrument platforms and process scale for both techniques
• Combines comprehensive coverage of both techniques in one volume
• Edited and authored by leading chromatography and extraction experts
• Contains over 200 figures and tables for clarity and key concept retention
• Showcases applications in environmental monitoring, food, natural products, forensic science, petrochemicals, pharmaceuticals, and bioanalysis