In this book, complementary knowledge about the structural and dynamical properties of rRNA secondary motifs (e.g. Kink-turn motifs, GTPase associated center, 16S Helix 44, A-site finger) is presented with prime focus on their intrinsic dynamical properties and related biological functions. The performed molecular dynamics studies provided detailed insight into the structure, dynamics, cation binding, hydration, and molecular interactions of selected rRNA motifs on the nanosecond time scale.