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Stem Cell Labeling for Delivery and Tracking Using Noninvasive Imaging: Series in Medical Physics and Biomedical Engineering

Editat de Dara L. Kraitchman, Joseph Wu
en Limba Engleză Hardback – 18 noi 2011
Stem Cell Labeling for Delivery and Tracking Using Noninvasive Imaging provides a comprehensive overview of cell therapy imaging, ranging from the basic biology of cell therapeutic choices to the preclinical and clinical applications of cell therapy. It emphasizes the use of medical imaging for therapeutic delivery/targeting, cell tracking, and determining therapeutic efficacy.
The book first presents background information and insight on the major classes of stem and progenitor cells. It then describes the main imaging modalities and state-of-the-art techniques that are currently employed for stem cell tracking. In the final chapters, leading scholars offer clinical perspectives on existing and potential uses of stem cells as well as the impact of image-guided delivery and tracking in major organ systems.
Through clear descriptions and color images, this volume illustrates how noninvasive imaging is used to track stem cells as they repair damaged tissue in the body. With contributions from some of the most prominent preclinical and clinical researchers in the field, the book helps readers to understand the evolving concepts of stem cell labeling and tracking as the field continues to move forward.
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Specificații

ISBN-13: 9781439807514
ISBN-10: 1439807515
Pagini: 490
Ilustrații: 16-page/32 figure color insert follows pg 202; 14 Equations 1 in text box; 21 Tables, black and white; 32 Illustrations, color; 143 Illustrations, black and white
Dimensiuni: 156 x 234 x 33 mm
Greutate: 0.82 kg
Ediția:1
Editura: CRC Press
Colecția CRC Press
Seria Series in Medical Physics and Biomedical Engineering


Public țintă

Health professionals, including radiologists, neurologists, cardiologists, surgeons, biomedical engineers, chemists, biologists, chemical engineers, medical physicists, materials scientists, and tissue engineers; senior undergraduate and graduate students in biomedical engineering, medical imaging, and materials science

Cuprins

Introduction: Stem Cell Types Overview and Rationale for Labeling for Imaging. Human Embryonic Stem Cells. Mesenchymal Stem Cells from Bone Marrow. Hematopoietic Stem Cells. Adipose-Derived Adult Stem Cells. Umbilical Cord Stem Cells. Induced Pluripotent Stem Cells. Radionuclide Approaches to Imaging Stem Cells and Their Biological Effects on the Myocardium. Fluorescence Imaging of Stem Cells In Vivo: Evolving Technologies and Applications. Ultrasound Imaging Basics. MRI Basics and Principles for Cellular Imaging. X-Ray Imaging Basics. Radionuclide Cell-Labeling Methods. Principles of Bioluminescence Imaging and Its Application In Vivo. Quantum Dot Labeling Methods. Magnetic Resonance Imaging Cell-Labeling Methods. Ultrasound Cell-Labeling Methods. X-Ray-Guided Delivery and Tracking of Cells. Multimodality/Fusion Imaging toward Imaging of Structure and Function. Other Non-Stem Cell Therapies for Cellular Tracking—Inflammatory Cell Tracking. Bioluminescence, MRI, and PET Imaging Modalities of Stem Cell-Based Therapy for Neurological Disorders. Clinical Application of Noninvasive Molecular Imaging in Cancer Cell Therapy: The First Reporter Gene-Based Imaging Clinical Trial. Clinical Cardiology Stem Cell Applications. Musculoskeletal Clinical Applications of Stem Cells. Regulatory Hurdles to Translation. Index.

Notă biografică

Dara L. Kraitchman, VMD, PhD, FACC, is an associate professor in the Department of Radiology and Department of Molecular and Comparative Pathobiology at Johns Hopkins University. Her research interests include noninvasive imaging and minimally invasive treatment of cardiovascular disease.
Joseph C. Wu, MD, PhD, is an associate professor in the Department of Medicine (Cardiology) and Department of Radiology at Stanford University School of Medicine. His research interests include stem cell biology, gene therapy, genomics, and molecular imaging.

Descriere

A comprehensive overview of cell therapy imaging, this book emphasizes the use of medical imaging for therapeutic delivery/targeting, cell tracking, and determining therapeutic efficacy. It presents background information and insight on the major classes of stem and progenitor cells and describes the main imaging modalities and state-of-the-art techniques currently employed for stem cell tracking. The book also offers clinical perspectives on existing and potential uses of stem cells as well as the impact of image-guided delivery and tracking in major organ systems.