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Statistical Analysis of Microbiome Data with R de Yinglin Xia

Statistical Analysis of Microbiome Data with R: ICSA Book Series in Statistics

Autor Yinglin Xia, Jun Sun, Ding-Geng Chen
en Limba Engleză Hardback – 20 oct 2018
This unique book addresses the statistical modelling and analysis of microbiome data using cutting-edge R software. It includes real-world data from the authors’ research and from the public domain, and discusses the implementation of R for data analysis step by step. The data and R computer programs are publicly available, allowing readers to replicate the model development and data analysis presented in each chapter, so that these new methods can be readily applied in their own research.
The book also discusses recent developments in statistical modelling and data analysis in microbiome research, as well as the latest advances in next-generation sequencing and big data in methodological development and applications. This timely book will greatly benefit all readers involved in microbiome, ecology and microarray data analyses, as well as other fields of research.
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Specificații

ISBN-13: 9789811315336
ISBN-10: 9811315337
Pagini: 532
Ilustrații: XXIII, 505 p. 84 illus., 67 illus. in color.
Dimensiuni: 160 x 241 x 34 mm
Greutate: 0.92 kg
Ediția:1st ed. 2018
Editura: Springer
Colecția ICSA Book Series in Statistics
Seria ICSA Book Series in Statistics

Locul publicării:Singapore, Singapore

Cuprins

Chapter 1: Introduction to R, RStudio and ggplot2.- Chapter 2: What are Microbiome Data?.- Chapter 3: Bioinformatic and Statistical Analyses of Microbiome Data.- Chapter 4: Power and Sample Size Calculation in Hypothesis Testing Microbiome Data.- Chapter 5: Microbiome Data Management.- Chapter 6: Exploratory Analysis of Microbiome Data.- Chapter 7: Comparisons of Diversities, OTUs and Taxa among Groups.- Chapter 8: Community Composition Study.- Chapter 9: Modeling Over-dispersed Microbiome Data.- Chapter 10: Linear Regression Modeling metadata.- Chapter 11: Modeling Zero-Inflated Microbiome Data.

Recenzii

“Statistical Analysis of Microbiome Data With R represents a very good foundational resource for bioinformaticians and statisticians interested in this emerging area of research.” (Kim-Anh Lê Cao, Biometrical Journal, Vol. 61, 2019)

Textul de pe ultima copertă

This unique book addresses the statistical modelling and analysis of microbiome data using cutting-edge R software. It includes real-world data from the authors’ research and from the public domain, and discusses the implementation of R for data analysis step by step. The data and R computer programs are publicly available, allowing readers to replicate the model development and data analysis presented in each chapter, so that these new methods can be readily applied in their own research.
The book also discusses recent developments in statistical modelling and data analysis in microbiome research, as well as the latest advances in next-generation sequencing and big data in methodological development and applications. This timely book will greatly benefit all readers involved in microbiome, ecology and microarray data analyses, as well as other fields of research.

Caracteristici

Written by experts actively engaged in the field Includes timely discussions and presentations on methodological development in microbiome studies and real-world applications Includes data and computer programs that are publicly available, allowing readers to replicate the statistical analyses Offers a framework for analysing microbiome data

Notă biografică

Dr. Yinglin Xia is a Research Professor in the Department of Medicine at the University of Illinois Chicago (UIC). He was a Research Assistant Professor in the Department of Biostatistics and Computational Biology at the University of Rochester (Rochester, NY) and Clinical Statistician in AbbVie (North Chicago, IL) before joining UIC as a Research Associate Professor in 2015. Dr. Xia has published more than 140 statistical methodology and research papers in peer-reviewed journals. He serves on the editorial board for several scientific journals including as an Associate Editor of Gut Microbes and has served as a reviewer for over 100 scientific journals. He is the lead authors of Statistical Analysis of Microbiome Data with R (Springer Nature, 2018), which was the first statistics book in microbiome study, Statistical Data Analysis of Microbiomes and Metabolomics(American Chemical Society, 2022) and An Integrated Analysis of Microbiomes and Metabolomics (American Chemical Society, 2022). Dr. Jun Sun is a tenured Professor of Medicine at the University of Illinois Chicago. She is an elected fellow of the American Gastroenterological Association (AGA) and American Physiological Society (APS). She chairs the AGA Microbiome and Microbial Therapy section. She is an internationally recognized expert on microbiome and human diseases, such as vitamin D receptor in inflammation, dysbiosis and intestinal dysfunction in amyotrophic lateral sclerosis (ALS). Her lab is the first to discover chronic effects and molecular mechanisms of Salmonella infection and development of colon cancer. Dr. Sun has published over 210 scientific articles in peer-reviewed journals and 8 books on microbiome. She is on the editorial boards of more than 10 peer-reviewed international scientific journals, including a Deputy Editor for American Journal of Physiology-GIL, an AssociateEditor for Gut Microbes. She serves on the study sections for the national and international research foundations.