Smart Healthcare 2.0: Integrating Digital Twins with AI-Driven Predictive Analytics offers a ground-breaking exploration of how digital twin technology, combined with real-time sensing and predictive analytics, is transforming healthcare delivery. As the global healthcare landscape shifts toward proactive, personalized care, this book addresses the urgent need for comprehensive resources that unify artificial intelligence, Internet of Things (IoT), and biomedical engineering within the digital twin framework. It provides an essential guide for researchers, engineers, and clinicians aiming to harness virtual patient models and data-driven insights to improve health outcomes and system efficiency in the era of ubiquitous healthcare.

This volume covers a wide spectrum of topics, starting with foundational concepts of digital twins in precision health and advancing through smart sensing technologies, scalable system architectures, and AI-powered predictive analytics. Readers will explore detailed discussions on edge-cloud computing, secure communication protocols including blockchain, and simulation platforms that enable virtual patient modeling. The book also addresses critical themes such as chronic disease management, emergency response optimization, ethical AI deployment, interoperability standards, and workforce readiness. Real-world case studies and future-focused chapters on cognitive twins and quantum simulation provide a rich, multidisciplinary perspective. Each chapter is complemented by pedagogical tools and supported by a companion website offering extended resources for teaching and applied research. Researchers and academics will find a consolidated, interdisciplinary framework linking theory with practical healthcare applications, ideal for advancing scholarship and innovation.

Biomedical and clinical engineers gain actionable insights into system design, sensor integration, and clinical validation for building reliable, patient-centered solutions. Healthcare AI engineers and data scientists will benefit from specialized guidance on deploying predictive models, managing multi-sensor data fusion, and ensuring privacy-compliant, real-time analytics. This book empowers stakeholders across the healthcare ecosystem to drive the next generation of intelligent, adaptive, and trustworthy digital health systems.

• Bridges AI, IoT, and biomedical engineering for comprehensive digital twin healthcare system design and deployment
• Offers practical frameworks for secure, scalable, and real-time patient monitoring and predictive health interventions
• Integrates ethical, legal, and interoperability considerations to ensure trustworthy and clinically relevant healthcare solutions
• Provides case studies and simulation tools to support research, education, and innovation in smart healthcare technologies