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Signaling Pathways for Translation: Stress, Calcium, and Rapamycin: Progress in Molecular and Subcellular Biology, cartea 27

Editat de Robert E. Rhoads
en Limba Engleză Paperback – 15 dec 2010
This volume presents the response of the eukaryotic translational apparatus to cellular stress and apoptosis, including kinases activated through both the ERK and stress-activated pathways. It further explores two agents that inhibit protein synthesis, calcium and the immunosuppressant rapamycin. Six chapters written by leading experts in the field provide both new data and comprehensive literature reviews. Both the regulation of initiation and elongation are discussed, and the mechanisms of apoptosis are related to changes in the protein synthesis machinery.
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Specificații

ISBN-13: 9783642075056
ISBN-10: 3642075053
Pagini: 188
Ilustrații: X, 178 p.
Dimensiuni: 155 x 235 x 10 mm
Greutate: 0.27 kg
Ediția:Softcover reprint of hardcover 1st ed. 2001
Editura: Springer Berlin, Heidelberg
Colecția Springer
Seria Progress in Molecular and Subcellular Biology

Locul publicării:Berlin, Heidelberg, Germany

Public țintă

Research

Cuprins

The Regulation of eIF4F During Cell Growth and Cell Death.- Regulation of the Activity of Eukaryotic Initiation Factors in Stressed Cells.- Initiation Factor eIF2? Phosphorylation in Stress Responses and Apoptosis.- Elongation Factor-2 Phosphorylation and the Regulation of Protein Synthesis by Calcium.- Phosphorylation of Mammalian eIF4E by Mnk1 and Mnk2: Tantalizing Prospects for a Role in Translation.- Control of Translation by the Target of Rapamycin Proteins.

Textul de pe ultima copertă

This volume presents the response of the eukaryotic translational apparatus to cellular stress and apoptosis, including kinases activated through both the ERK and stress-activated pathways. It further explores two agents that inhibit protein synthesis, calcium and the immunosuppressant rapamycin. Six chapters written by leading experts in the field provide both new data and comprehensive literature reviews. Both the regulation of initiation and elongation are discussed, and the mechanisms of apoptosis are related to changes in the protein synthesis machinery.

Caracteristici

An up-to-date overview of the effects of stress and apoptosis on translation Includes supplementary material: sn.pub/extras