This safety evaluation report (SER) documents the technical review of the R.E. Ginna Nuclear Power Plant (Ginna) license renewal application (LRA) by the U.S. Nuclear Regulatory Commission staff (staff). By letter dated July 30, 2002, Rochester Gas & Electric Corporation (RG&E or the applicant) submitted the LRA for Ginna in accordance with Title 10, Part 54, of the Code of Federal Regulations (10 CFR Part 54 or the Rule). Through that LRA, RG&E requested that the U.S. Nuclear Regulatory Commission (NRC) renew the operating license for Ginna (license number DPR-18) for a period of 20 years beyond the current expiration of midnight, September 18, 2009.