Reproducibility in Biomedical Research: Epistemological and Statistical Problems, Second Edition explores the ideas and conundrums inherent in scientific research. This second edition addresses new challenges to reproducibility in biosciences, namely reproducibility of machine learning Artificial Intelligence (AI), reproducibility of translation from research to medical care, and the fundamental challenges to reproducibility. All current chapters are expanded to cover advances in the topics previously addressed. This book provides biomedical researchers with a framework to better understand the reproducibility challenges in the area. Newly introduced interactive exercises and updated case studies help students understand the fundamental concepts involved in the area.

• Includes four new chapters and updates across the book, covering recent developments of issues affecting reproducibility in biomedical research
• Covers reproducibility of results from machine learning AI algorithms
• Presents new case studies to illustrate challenges in related fields
• Includes a companion website with interactive exercises and summary tables