In this issue of Urologic Clinics of North America, guest editors Drs. Hanan Goldberg and Gennady Bratslavsky bring their considerable expertise to the topic of Current Management of Localized Prostate Cancer. Top experts explore recent, significant investigation and research into various aspects of the assessment and management of clinically localized disease, which has led to novel findings and ideas regarding diagnostic, imaging, pathological, genetic, and therapeutic interventions for prostate cancer.