Quantitative Biology: From Molecular to Cellular Systems: Chapman & Hall/CRC Mathematical Biology Series
Editat de Michael E. Wallen Limba Engleză Hardback – 25 aug 2012
The book is organized into three sections:
- Fundamental Concepts covers bold ideas that inspire novel approaches in modern quantitative biology. It offers perspectives on evolutionary dynamics, system design principles, chance and memory, and information processing in biology.
- Methods describes recently developed or improved techniques that are transforming biological research. It covers experimental methods for studying single-molecule biochemistry, small-angle scattering from biomolecules, subcellular localization of proteins, and single-cell behavior. It also describes theoretical methods for synthetic biology and modeling random variations among cells.
- Molecular and Cellular Systems focuses on specific biological systems where modern quantitative biology methods are making an impact. It incorporates case studies of biological systems for which new concepts or methods are increasing our understanding. Examples include protein kinase at the molecular level, the genetic switch of phage lambda at the regulatory system level, and Escherichia coli chemotaxis at the cellular level.
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Specificații
ISBN-13: 9781439827222
ISBN-10: 1439827222
Pagini: 392
Ilustrații: 132
Dimensiuni: 178 x 254 x 25 mm
Greutate: 0.84 kg
Ediția:New.
Editura: CRC Press
Colecția CRC Press
Seria Chapman & Hall/CRC Mathematical Biology Series
ISBN-10: 1439827222
Pagini: 392
Ilustrații: 132
Dimensiuni: 178 x 254 x 25 mm
Greutate: 0.84 kg
Ediția:New.
Editura: CRC Press
Colecția CRC Press
Seria Chapman & Hall/CRC Mathematical Biology Series
Cuprins
Free Energies, Landscapes, and Fitness in Evolution Dynamics. System Design Principles. Chance and Memory. Information Theory and Adaptation. Quantitative In Vitro Biochemistry, One Molecule at a Time. Small-Angle Scattering. Subcellular Signaling Dynamics. Single-Cell Behavior. Modeling Genetic Parts for Synthetic Biology. Modeling Cellular Variability. PKA: Prototype for Dynamic Signaling in Time and Space. Stochastic Simulation of the Phage Lambda Gene Regulatory Circuitry. Chemotaxis.
Notă biografică
Michael E. Wall is with the Computer, Computational, and Statistical Sciences Division of the Los Alamos National Laboratory in New Mexico.
Descriere
Providing an overview of quantitative biology, this book presents practical tools for the observation, modeling, design, and manipulation of biological systems from the molecular to cellular levels. The book offers an introduction to fundamental concepts and computational, mathematical, and experimental studies of molecular and cellular behavior. The first section of the text covers basic, integrative concepts that form the foundation of the field. The next section reviews state-of-the-art methods in quantitative biology and case studies of specific systems. The last section focuses on important biological systems where modern quantitative methods are making an impact.