The cutting-edge Purine and Pyrimidine Metabolism in Man IX brings together contributions from internationally recognized researchers in the fields of molecular genetics, biochemical pharmacology, biochemistry, developmental biology, immunology, and epidemiology. This research has been crucial for the develoment of potent anticancer and antiviral drugs. A sampling of topics includes -- gout -- adenosine -- inborn errors of purine and pyrimidine metabolism -- mutations -- effects of hypoxia, free radicals, or reperfusion injury -- hot research areas, and -- cell differentiation and malignancies.