Cantitate/Preț
Produs
Total produse
Vezi coșul
Pulmonary Hypertension de Bradley A. Maron

Pulmonary Hypertension

Editat de Bradley A. Maron, Roham T. Zamanian, Aaron B. Waxman
en Limba Engleză Hardback – 10 noi 2015

Adresat specialiștilor în cardiologie, pneumologie și medicină internă, precum și rezidenților dornici de aprofundare, Pulmonary Hypertension reprezintă o sinteză clinică și științifică de înalt nivel. Găsim în această primă ediție publicată de Springer un cadru de referință pentru înțelegerea unei patologii complexe, caracterizată prin remodelarea arteriolelor distale și creșterea rezistenței vasculare. Descoperim o structură riguroasă care pornește de la nomenclatura istorică și genetica bolii vasculare pulmonare, avansând către mecanisme inovatoare precum biologia de rețea și semnalizarea MicroRNA. Suntem de părere că forța acestui volum rezidă în capacitatea de a acoperi lacuna dintre cercetarea translațională și practica clinică, oferind protocoale detaliate pentru evaluarea hemodinamică cardiopulmonară și tehnici de imagistică avansată.

În ceea ce privește contextul bibliografic, acolo unde Pathophysiology of Pulmonary Hypertension de Yuansheng Gao se concentrează pe mecanismele de semnalizare și contractilitate vasculară, volumul de față extinde perspectiva, tratând hipertensiunea pulmonară și ca o boală metabolică și neurohumorală, implicând sistemul renină-angiotensină-aldosteron. De asemenea, spre deosebire de abordările pur clinice, această lucrare subliniază importanța modelelor animale în înțelegerea patogenezei. Progresia capitolelor este logică, facilitând tranziția de la epidemiologie la biomarcatori și metode de evaluare a stării bolii în cercetare, oferind astfel instrumentele necesare pentru gestionarea unui număr tot mai mare de pacienți eligibili pentru noile farmacoterapii selective.

Citește tot Restrânge

Preț: 123949 lei

Preț vechi: 130473 lei
-5%

Puncte Express: 1859
Paperback 83290 lei
Hardback 123949 lei

Carte tipărită la comandă

Livrare economică 30 mai-05 iunie

 Adaugă în coș

Wish list
Gift list
Am citit!
Adaugă în listă

Specificații

ISBN-13: 9783319235936
ISBN-10: 3319235931
Pagini: 388
Ilustrații: XVI, 371 p.
Dimensiuni: 215 x 285 x 26 mm
Greutate: 1.31 kg
Ediția:1st edition 2016
Editura: Springer
Locul publicării:Cham, Switzerland

Public țintă

Professional/practitioner

De ce să citești această carte

Recomandăm această carte medicilor care tratează insuficiența cardiacă și patologiile respiratorii cronice. Cititorul câștigă o înțelegere profundă a cuplajului ventricul drept-circulație pulmonară, esențială pentru diagnosticul precoce. Este un instrument indispensabil pentru a naviga prin complexitatea noilor tratamente selective și a tehnicilor de monitorizare hemodinamică, traduse din cercetarea translațională direct în practica de cabinet.

Despre autor

Bradley A. Maron, Roham T. Zamanian și Aaron B. Waxman sunt autorități recunoscute în domeniul medicinei vasculare și pulmonare, activând în instituții academice de prestigiu. Expertiza lor combinată acoperă spectrul complet al hipertensiunii pulmonare, de la cercetarea de laborator și studiile genetice, până la managementul clinic al pacienților cu afecțiuni cardiopulmonare complexe. Contribuția lor ca editori asigură o rigoare științifică deosebită, integrând cele mai recente descoperiri despre remodelarea vasculară și funcția ventriculară în protocoale clinice aplicabile.

Descriere scurtă

This book provides the framework for a singular reference in the field of pulmonary hypertension. Pulmonary vascular disease is a complex and heterogeneous condition characterized by remodeling of distal pulmonary arterioles that increases pulmonary vascular resistance to affect cardiopulmonary hemodynamic and right ventricular function adversely, resulting in a clinical syndrome of diminished exercise tolerance, shortness of breath, and heart failure-associated morbidity and mortality. Owing to the availability of novel pulmonary circulation-selective pharmacotherapies over the previous decade, the number of pulmonary hypertension patients eligible for treatment has increased substantially. Despite this progress, under-awareness persists within the practicing pulmonary, cardiovascular, and general internal medicine communities. This is due, in part, to the complex array of molecular mechanisms implicated in the pathobiology of PH, as well as cutting-edge discoveries from translationalscientific works that provide a new framework by which to understand pulmonary vascular-right ventricular coupling. Taken together, a key educational opportunity is exposed to bridge this knowledge gap through the synthesis of a contemporary text that emphasizes basic science, translational and clinical principles, and treatment strategies for understanding pulmonary hypertension.

Cuprins

Historical Perspective on the Classification and Nomenclature of Pulmonary Hypertension.- The Defining Characteristics of Pulmonary Arterial Hypertension.- Pulmonary Hypertension in Patients Without Pulmonary Arterial Hypertension.- Epidemiology of Pulmonary Hypertension: From Quaternary Referral Centre to the Community.- The Effects of Chronic Hypoxia on Inflammation and Pulmonary Vascular Function.- Genetics of Pulmonary Vascular Disease.- Novel Mechanisms of Disease: Network Biology and MicroRNA Signaling in Pulmonary Hypertension.- Pulmonary Hypertension as a Metabolic Disease.- Renin-Angiotensin-Aldosterone and other Neurohumoral Factors in the Pathogenesis of Pulmonary Hypertension.- Animal Models of Pulmonary Hypertension.- The Cardiopulmonary Hemodynamic Evaluation of Pulmonary Hypertension.- Advanced Imaging in Pulmonary Hypertension.- Assessing Disease State in the Pulmonary Vasculature in Clinical Practice and Research.- Biomarkers and other Methods for Assessing Patient Progress.- Pulmonary Circulatory - Right Ventricular Uncoupling: New Insights into Pulmonary Hypertension Pathophysiology.- Contemporary Pharmacotherapies Involving Nitric Oxide, Prostacyclin, and Endothelin Receptor Signaling Pathways.- Determining the Optimal Approach to Initiating Oral, Inhaled, and Intravenous Therapies in Clinical Practice: Sequential Goal-Directed Therapy is Best.- Counterpoint: Determining the optimal approach to initiating oral, inhaled, and intravenous therapies in clinical practice: Maximal upfront therapy is best.- Surgery, Devices, Transplantation and Other Interventional Options for the Treatment of Advanced Pulmonary Hypertension.- Patient Registries in Pulmonary Arterial Hypertension:  the Role of Survival Equations and Risk Calculators.- Support Care for the Pulmonary Hypertension Patient.- Special Considerations for the Pulmonary Hypertension Patient.- The Future of Pulmonary Hypertension.

Recenzii

“This is a comprehensive book on the important clinical topic of pulmonary hypertension, and one of the most up to date on this emerging field of study. … The intended audience is specialists in the field of cardiology and pulmonology. … This book is useful for both clinicians and those interested in basic science and translational research.” (Shubhum Misra, Doody's Book Reviews, February, 2016)

Notă biografică

Bradley A. Maron, M.D. is an Assistant Professor of Medicine at Harvard Medical School (HMS), Associate Physician in the Division of Cardiovascular Medicine at Brigham and Women’s Hospital, and Co-director of the Pulmonary Vascular Disease Center at the Boston VA Healthcare System. His research focuses on the basic mechanisms underpinning adverse pulmonary vascular remodeling. Dr. Maron’s research is funded by the NIH, among other prestigious foundations. He is also an Eleanor and Miles Shore Scholar in Medicine and HMS Excellence in Teaching award recipient.
 
Roham T. Zamanian, M.D. is an Assistant Professor of Medicine and Director of the Adult Pulmonary Hypertension Program at Stanford University School of Medicine.  Dr. Zamanian completed medical school and Internal Medicine training at the University of California, Irvine Medical Center and fellowship in Pulmonary and Critical Care Medicine at Stanford University.  Dr. Zamanian was also an eBay Pulmonary Vascular Disease super-fellow at the Vera Moulton Wall Center (VMWC) for Pulmonary Vascular Diseases at Stanford University.  Besides an active clinical career, Dr. Zamanian is a translational scientist focusing on the discovery of novel biochemical and clinical risk factors for pulmonary vascular disease.  Dr. Zamanian’s research is funded by the NIH and VMWC.    Aaron Waxman, M.D., Ph.D., is the Executive Director of the Center for Pulmonary Heart Diseases at the Brigham and Women’s Hospital (BWH) Heart and Vascular and Lung Centers. Dr. Waxman directs the Pulmonary Vascular Disease Program at BWH.  His interests focus on integrating clinical and basic investigations to understand further pulmonary vascular disease and right heart failure. Dr. Waxman directs a robust NIH-funded clinical and basic research program, posts leadership roles in several international organizations, and collaborates actively with clinical experts and investigators around the world.
 

Textul de pe ultima copertă

This definitive textbook details the rapid advances in epidemiology, pathobiology and therapeutics in the field of pulmonary hypertension. Despite recent progress, under-awareness persists within the practicing pulmonary, cardiovascular, and general internal medicine communities. This is due, in part, to the complex array of molecular mechanisms implicated in the pathobiology of PH, as well as cutting-edge discoveries from translational scientific works that provide a new framework by which to understand pulmonary vascular-right ventricular coupling. This book bridges this knowledge gap through the synthesis of a contemporary text that emphasizes basic science, translational and clinical principles, and treatment strategies for understanding pulmonary hypertension.
Pulmonary Hypertension: Basic Science to Clinical Medicine is the essential reference for any physician or scientist with an interest in pulmonary hypertension. The Editors and their hugely knowledgeable listof contributors have provided a contemporary, comprehensive overview of the field in all of its complexity that will be vital for all levels of clinician, researcher and trainee in respiratory medicine, cardiology, critical care and all disciplines involved in the management of patients with pulmonary hypertension.

Caracteristici

Emphasizes basic mechanisms of disease, translational and clinical principles of pulmonary hypertension and right ventricular dysfunction Discusses controversies in PH disease management to provide the readership with balanced opinions on hot topics in the field Serves as the state of the art text in pulmonary vascular disease by providing a comprehensive review of each pertinent and cutting-edge principle material to scientific to clinical domains within the field?