Progress in Molecular and Subcellular Biology de Philippe Jeanteur

Progress in Molecular and Subcellular Biology

Philippe Jeanteur

Biological functions are almost exclusively attributed to macromolecules, i.e. nucleic acids, proteins and polysaccharides. To gain their complete functional activities these biomolecules have to associate with the nuclear matrix, the cytoskeleton and the cell/plasma membranes. It is the aim of this series to discuss actual aspects in the field of structure-associated genetic and epigenetic functional processes. This series of survey reviews fills the gap in structure-associated information flow, and is a vital reference work for scientists in molecular and cell biology.

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	Preț	Express
Paperback (2)	610^.47 lei 6-8 săpt.
Springer – 6 dec 2011	610^.47 lei 6-8 săpt.
Springer Berlin, Heidelberg – 23 dec 2011	611^.12 lei 6-8 săpt.

Preț

Express

Paperback (2)

610^.47 lei 6-8 săpt.

Springer – 6 dec 2011

610^.47 lei 6-8 săpt.

Springer Berlin, Heidelberg – 23 dec 2011

611^.12 lei 6-8 săpt.

Cuprins

Synthesis of Small Nuclear RNAs.- 1 Introduction.- 2 Two Classes of U snRNA Genes.- 3 RNA Polymerases Transcribing U snRNA Genes.- 4 Organization of U snRNA Genes.- 5 Cis-Acting Elements in U snRNA Genes.- 6 Interconversion of U snRNA Promoters.- 7 Regulation of snRNA Synthesis.- 8 Formation of Cap Structure in U snRNAs.- 9 Summary.- References.- The DNA-Activated Protein Kinase, DNA-PK.- 1 Nuclear Protein Kinases.- 2 Nucleic Acid Effects on Protein Kinase Activity.- 3 Detection of DNA-Stimulated Protein Phosphorylation in Cell Extracts.- 4 Purification of DNA-PK from HeLa Cells.- 5 Physical Characteristics of DNA-PK.- 6 Subcellular Localization.- 7 Phosphate Donor and Cofactor Requirements.- 8 Effects of Inhibitors.- 9 Substrate Specificity.- 10 Effects of Polynucleotides.- 11 Occurrence of DNA-PK in Other Cells.- 12 Comparison with Other Nuclear Protein Kinases.- 13 Conclusions and Future Directions.- References.- The Cytoskeleton During Early Development: Structural Transformation and Reorganization of RNA and Protein.- 1 Introduction.- 2 The Cytoskeleton in the Early Development of Chordates.- 3 The Cytoskeleton in the Early Development of Nonchordates.- 4 Conclusion.- References.- Developmental Regulations of Heat-Shock Protein Synthesis in Unstressed and Stressed Cells.- 1 Introduction.- 2 Expression of Heat-Shock Genes During Gametogenesis and Early Development in the Absence of Stress.- 3 Heat-Shock Protein Synthesis in Differentiation Processes.- 4 Deficient Heat-Shock Responses.- 5 Concluding Remarks.- References.- The Interactions of Water and Proteins in Cellular Function.- 1 Introduction.- 2 The Cluster Model of Liquid Structure.- 3 The Domain Model of Protein Structure.- References.