Isaac Newton's book Principia set a scientific paradigm focused on that which is deterministic and physical. Starting with Einstein the scientific paradigm shifted to that which is more observer / time focused, i.e. relativistic as well as probabilistic. This book, Principia 2.0, takes the next step towards a new scientific paradigm that will help scientists and inquiring minds deal with recently discovered dark matter / energy, which makes up 95.1% of the universe and is the big mystery of modern science. This is a mid-level book written for both scientists and inquiring minds looking to expand their scientific horizons. To that end the book is between entertaining narrative and mind numbing equation-centric. There are few equations in this book but many visual diagrams. This book develops many ground breaking new concepts and theories (General Projective Relativity or GPR) pertaining to quantum, cosmological, and Complex Adaptive Systems science.