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Predictive Approaches in Drug Discovery and Development de J Andrew Williams

Predictive Approaches in Drug Discovery and Development

Editat de J Andrew Williams, Richard Lalonde, Jeffrey R Koup, David D Christ, Sean Ekins
en Limba Engleză Hardback – 10 apr 2012
Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and development and contains state-of-the-art appraisals on the practical utility of genomic, biochemical, and protein biomarkers. Case histories and lessons from successful and unsuccessful applications of biomarkers are included along with key chapters on GLP validation, safety biomarkers and proteomics biomarkers. Regulatory agency perspectives and initiatives both in the US and internationally are also discussed.
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Specificații

ISBN-13: 9780470170830
ISBN-10: 0470170832
Pagini: 416
Dimensiuni: 161 x 240 x 26 mm
Greutate: 0.78 kg
Editura: Wiley
Locul publicării:Hoboken, United States

Public țintă

Pharmaceutical scientists pursing drug research and development, including management, bench–level pharmacologists, and toxicologists; Clinical pharmacologists and clinicians, ADME/Tox and pharmaceutical scientists and students; Pharmaceutical companies interested in improving decision making and reducing costs; Regulatory agencies like the US FDA and EPA, British MHRA, and other European and Japanese equivalents.

Notă biografică

J. Andrew Williams, PHD, is Director of Translational Oncology at Pfizer Oncology. Richard Lalonde, PharmD, is Vice President and Global Head of Clinical Pharmacology at Pfizer. Jeffrey Koup, PharmD, is a consultant for PKPD modeling and the owner of Lakeside PKPD, LLC. David D. Christ, PHD, is a consultant with SNC Partners LLC.

Descriere

Practical Utility of Biomarkers in Drug Discovery and Development covers all aspects of biomarker research applied to drug discovery and development and contains state-of-the-art appraisals on the practical utility of genomic, biochemical, and protein biomarkers.