Since Gutenberg's time, every aspect of print has gradually changed. But the advent of computational media has exponentially increased the pace, transforming how books are composed, designed, edited, typeset, distributed, sold, and read. N. Katherine Hayles traces the emergence of what she identifies as the postprint condition, exploring how the interweaving of print and digital technologies has changed not only books but also language, authorship, and what it means to be human. Hayles details the consequences for humanities publications through interviews with scholars and university press professionals and considers the cultural implications in readings of two novels, The Silent History and The Word Exchange, that explore the postprint condition. Spanning fields including book studies, cultural theory, and media archeology, Postprint is a strikingly original consideration of the role of computational media in the ongoing evolution of humanity.