Pig's Knuckle is the story of two friends and flatmates called Macca and Lulu and their working lives and personal problems. Lulu leads a quiet life before surprising her flatmate Macca by becoming a Senator in the Australian Parliament. She is involved in a scandal and confronts a hostile, unfair media, as well as unhelpful fellow politicians. After becoming a politician, Lulu also begins dating a man named Ross, much to Macca's chagrin. This is the story of two friends and where life takes them as they confront challenges that make them stronger and bring them closer together.