In this issue of Surgical Pathology Clinics, guest editor Dr. Alyaa Al-Ibraheemi brings her considerable expertise to the topic of Pediatric Pathology: Emerging Entities, Current Trends, and Comprehensive Updates. Top experts help readers understand the latest developments and emerging entities in the field of pediatric pathology and gain comprehensive knowledge of the diagnostic and clinical aspects of pediatric diseases. This issue also discusses how to differentiate and classify newly identified pediatric tumors and integrate the histologic, molecular, and cytogenetic findings in an integrated pathology report.