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Nicotinic Acetylcholine Receptor Technologies de Ming D. Li

Nicotinic Acetylcholine Receptor Technologies: Neuromethods, cartea 117

Editat de Ming D. Li
en Limba Engleză Paperback – 27 iun 2018
This volume provides properties, biological function, methods,and approaches for manipulating nAChRs in different organisms. NicotinicAcetylcholine Receptor Technologies guides readers through moleculartechniques and behavioral tests used to investigate nicotinic drugs,chronoamperometry, emerging technologies and methods for the analysis ofnAChRs, single nucleotide polymorphism (SNP), fluorescence techniques, spectralconfocal, allosteric modulators of a7-nAChRs, and a comprehensive evolutionalrelation for most nAChR subunits, in both vertebrate and invertebrate species.Written for the popular Neuromethods series, chapters include thekind of detail and key implementation advice that ensures successful results inthe laboratory.
 
Authoritative and practical, Nicotinic AcetylcholineReceptor Technologies aims to ensure successful results in thefurther study of this vital field.
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Specificații

ISBN-13: 9781493981335
ISBN-10: 1493981331
Pagini: 272
Ilustrații: XII, 259 p. 23 illus.
Dimensiuni: 178 x 254 x 15 mm
Greutate: 0.52 kg
Ediția:Softcover reprint of the original 1st edition 2016
Editura: Springer
Colecția Neuromethods
Seria Neuromethods

Locul publicării:New York, NY, United States

Cuprins

Analysisof Nicotinic Acetylcholine Receptor (nAChR) Gene Expression in the Zebrafish (Daniorerio)by In Situ Hybridization and PCR.- Zebrafish:An Animal Model to Study Nicotinic Drugs on Spatial Memory and VisualAttention.- ConditionedPlace Preference and Behavioral Analysis to Evaluate Nicotine ReinforcementProperties in Zebrafish.- Study of theContribution of Nicotinic Receptors to the Release of Endogenous BiogenicAmines in Drosophila Brain.- Emerging Technologiesin the Analysis of C. Elegans NicotinicAcetylcholine Receptors.-Using Natural GeneticVariability in Nicotinic Receptor Genes to Understand the Function of NicotinicReceptors.- Nicotinic Acetylcholine Receptors as Targetsfor Tobacco Cessation Therapeutics: Cutting-edge Methodologies to Understand Receptor Assembly andTrafficking.- Spectral Confocal Imaging to Examine Upregulation ofNicotinic Receptor Subunits in α4-Yellow Fluorescent Protein Knock-in Mice.- α7-nicotinicAcetylcholine Receptors: New Therapeutic Avenues in Alzheimer's Disease.-α7-nicotinic Acetylcholine Receptors and β-amyloid Peptides in Alzheimer'sDisease.- Developmentof Antidepressant Drugs Through Targeting a4β2-Nicotinic AcetylcholineReceptors.- Evolutionary Relationship of Nicotinic Acetylcholine Receptor Subunitsin Both Vertebrate and Invertebrate Species. 

Caracteristici

Includes cutting-edge methods and protocols Provides step-by-step details essential for reproducible results Contains key notes and implementation advice from the experts Includes supplementary material: sn.pub/extras