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NERVE GROWTH FACTOR: From Neuron Development to Neurology: Molecular Mediators in Health and Disease: How Cells Communicate

Editat de Antonino Cattaneo, Simona Capsoni
en Limba Engleză Paperback – iun 2026
Nerve growth factor: From Neuron Development to Neurology, the latest release in the Molecular Mediators in Health and Disease series, offers a complete guide to nerve growth factor (NGF) across health and disease. Sections cover key properties, the latest advances, and biomedical applications of this neuropeptide. The book begins with an introduction and historical overview of the discovery of NGF before exploring its molecular characteristics. It then covers NGF in organ function, with chapters discussing the brain, immune system, blood vessels, heart, reproductive organs, teeth, and lungs. NGF pharmacology is then considered, with a focus on NGF as a therapeutic agent.

The final section of the book covers NGF across diseases, including Alzheimer’s disease, cancer, diseases of the eye, chronic pain, and visceral disfunctions. Throughout the book, NGF is considered in the context of both mammalian and non-mammalian biology, making it an ideal reference for researchers working across the fields of cell biology, molecular biology, pharmacology, and other biomedical areas.

  • Explores the pathways of NGF, its receptors, and physiological functions
  • Covers NGF in disease, including neurodegenerative disease and cancer
  • Considers the therapeutic potential of NGF
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Specificații

ISBN-13: 9780443330889
ISBN-10: 0443330883
Pagini: 480
Dimensiuni: 191 x 235 mm
Editura: ELSEVIER SCIENCE
Seria Molecular Mediators in Health and Disease: How Cells Communicate


Cuprins

Part I - Introduction to Nerve Growth
1. History of Nerve Growth
2. Nerve Growth Factor in Normal Biology

Part II – Molecular biology of Nerve Growth
3. Production and structure of Nerve Growth
4. Measurement of Nerve Growth Factor and its precursor
5. Nerve Growth Factor receptors

Part III – Nerve Growth Factor in organ function
6. NGF in sensory and sympathetic neurons
7. NGF in Brain
8. NGF and the immune system
9. NGF in blood vessels and heart
10. NGF in reproductive organs
11. NGF in teeth
12. Nerve Growth Factor and the Lung.

Part IV – Nerve Growth Factor pharmacology
13. TrkA mimetics
14. P75NTR receptor blockers
15. Antibodies neutralizing NGF or TrkA
16. Nerve Growth Factor protein as a therapeutic agent

Part V – NGF in non-mammalian biology
17. NGF in non-mammalian organisms

Part VI - Nerve Growth Factor in Disease
18. Nerve Growth Factor and Alzheimer’s disease
19. Nerve Growth Factor and diseases of the eye
20. Nerve Growth factor and cancer
21. Nerve Growth Factor and chronic pain
22. Nerve Growth Factor and visceral disfunctions