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Mononuclear Phagocytes: Functional Aspects

Editat de R. van Furth
en Limba Engleză Paperback – 23 aug 2014
Sixteen years have passed since the first Leiden Conference on Mononuclear Phagocytes. That first meeting led to new nomenclature, i. e. , the Mononuclear Phagocytes System (MPS), which was published in the Bulletin of the World Health Organization (R. van Furth, et aI. , Bull. WHO, 1972, 46: 845-852). The paradigm of the MPS has the advantage of being much more consistent than the Reticuloendothelial System (RES) (L. Aschoff, Ergebn. Inn. Med. Kinderheilk. 1924, 26:1), because cells with similar characteristics can be classified in the same category. The essence ota new concept is, according to Popper, that it must be susceptible to falsification. This has been attempted several times for the MPS by those who adhere to the RES. However, in biology no one can be certain of truth. Any theory must be based on experimental observations and/or theoretical consider­ ations and both should be presented in such a way that others can try to refute it, then or later. One may have a theoretical or a pragmatic preference for a theory which at a given time is regarded as possibly truc, but later it may be shown to be false. In other words, what we present in this volume is regarded as true at this moment, but others may consider it as not true and try to disprove it. Controversies often stimulate new research.
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Specificații

ISBN-13: 9789400987951
ISBN-10: 9400987951
Pagini: 2052
Ilustrații: LXXIII, 1961 p. 262 illus. In 4 volumes, not available separately.
Dimensiuni: 155 x 235 x 108 mm
Ediția:Softcover reprint of the original 1st ed. 1980
Editura: SPRINGER NETHERLANDS
Colecția Springer
Locul publicării:Dordrecht, Netherlands

Public țintă

Research

Cuprins

1 Cells of the mononuclear phagocyte system Nomenclature in terms of sites and conditions.- 2 Peroxidase and catalase in monocytes, macrophages, epithelioid cells and giant cells of the rat.- 3 Changes in peroxidase distribution within organelles of blood monocytes and peritoneal macrophages after surface adherence in vitro and in vivo.- 4 Development of exudate-resident macrophages, on the basis of the pattern of peroxidatic activity in vivo and in vitro.- 5 The vacuolar apparatus of alveolar macrophages and the turnover of surfactant.- 6 Properties of Kupffer cells.- 7 Origin and structure of the osteoclast.- 8 Veiled cells resembling Langerhans cells.- 9 Characteristics, origin and kinetics of human and murine mononuclear phagocytes.- 10 The origin and properties of peripheral lymph mononuclear phagocytes.- 11 Humoral control of monocyte production during inflammation.- 12 Long-term cultures of murine bone marrow mononuclear phagocytes.- 13 Effector cell functions in long-term culture of murine, prosimian, and human bone marrow.- 14 Formation of colonies by mononuclear phagocytes outside the bone marrow.- 15 Regulation of macrophage production by a colony-stimulating factor.- 16 Functions of macrophage cell lines.- 17 Gradients of chemotactic factors in various assay systems.- 18 The locomotor behaviour of human blood monocytes in chemotactic and chemokinetic environments and the role of substratum in monocyte locomotion.- 19 Alteration of macrophage and monocyte membrane potential by chemotactic factors.- 20 MIF/MAF-macrophage interactions: biochemical characterization of a putative glycolipid receptor for MIF and the existence and properties of two distinct MIFs.- 21 Lymphokine-induced modulation of macrophage functions.- 22 An inhibitor of macrophage accumulationproduced by neoplasms: its role in abrogating host resistance to cancer.- 23 Membrane flow during endocytosis.- 24 Membrane recycling (shuttle?) in endocytosis.- 25 The iodination and turnover of macrophage plasma membrane polypeptides.- 26 Macrophage ecto-enzymes: their identification, metabolism, and control.- 27 Membrane lipids and the control of endocytosis.- 28 Surface functions in dividing macrophages.- 29 Fc receptors on mouse macrophages.- 30 Structural characteristics of Fc receptors on macrophages.- 31 Quantitative studies on the interaction of macrophages with antibody and immune complexes.- 32 Hormone receptors and hormonal regulation of macrophage physiological functions.- 33 In vivo and in vitro evidence for a lysosomal enzyme uptake system in macrophages.- 34 Cellular recognition by phagocytes: role of lectin-like receptor(s).- 35 Phagocytosis.- 36 Modulation of macrophage plasma membrane receptors for IgG and complement.- 37 Genetic and functional studies of continuous macrophage-like cell lines.- 38 Contractile proteins and the mechanism of phagocytosis in macrophages.- 39 Factors modifying the fusion of phagosomes and lysosomes: art, fact, and artefact.- 40 Manipulations of phagosome-lysosome fusion in cultured macrophages: potentialities and limitations.- 41 Cyclic nucleotides and phagosome-lysosome fusion in mouse peritoneal macrophages.- 42 Determinants of phagosome-lysosome fusion in mouse macrophages.- 43 Oxygen intermediates and the microbicidal event.- 44 Release of superoxide anion by macrophages: effect of in vivo or in vitro priming.- 45 The release of hydrogen peroxide from mononuclear phagocytes and its role in extracellular cytolysis.- 46 Oxidative metabolism of mononuclear phagocytes.- 47 The oxygen metabolism of human blood monocytes andneutrophils.- 48 Effects of oxygen on metabolic patterns and endocytosis of macrophages.- 49 Lysozyme and plasminogen activator: constitutive and induced secretory products of mononuclear phagocytes.- 50 Modulation of macrophage plasminogen activator secretion.- 51 The synthesis of arachidonic acid oxygenation products by various mononuclear phagocyte populations.- 52 Generation of tissue thromboplastin by human monocytes.- 53 Secretion of lysosomal enzymes by macrophages.- 54 Synthesis and release of complement components by macrophages.- 55 The stimulation of mononuclear phagocytes by components of the classical and the alternative pathways of complement activation.- 56 Complement, coagulation and mononuclear phagocytes.- 57 Extracellular stimulation of intracellular killing.- 58 Respiratory pathways of macrophages — cellular localization and relation to cidal activity.- 59 Macrophage activation by interferon or interferon inducers.- 60 Macrophage activation by IgE.- 61 The effect of complement on the degradation of soluble immune aggregates by Kupffer cells and peritoneal macrophages in vitro.- 62 Macrophage activation in vitro by phagocytosis.- 63 Induction of macrophage microbicidal activity.- 64 Interactions of macrophages with intravacuolar bacteria and protozoa.- 65 Cytotoxic and microbicidal properties of macrophages.- 66 Significance of systemic macrophage activation in response to tumor growth.- 67 Regulation of macrophage non-specific tumoricidal capability.- 68 Distinctive characteristics of host tumor resistance in a rat fibrosarcoma model system.- 69 Intracellular killing, degradation, metabolic activity, and increase in ?-galactosidase activity as markers for activated macrophages.- 70 Cytotoxicity of human monocytes against sensitized erythrocytes.-71 Dendritic cells and macrophages — current knowledge of their distinctive properties and functions.- 72 Reticulum cells and macrophages in the immune response.- 73 Multiple interactions between listeria-immune T lymphocytes and macrophages: regulation by the major histocompatibility gene complex.- 74 Role of macrophages in the in vitro induction and regulation of antibody responses.- 75 Physical and functional macrophage-lymphocyte interactions in antigen recognition by T lymphocytes.- 76 Expression of Ir genes and Ia antigens by adherent accessory cells required for antigen- specific antibody-forming cell responses.- 77 Summation.

Recenzii

`This book comprises the proceedings of the fourth Leiden conference... Anybody with more than a passing interest in mononuclear phagocyte cells will want to have these proceedings available for consultation. ...this is a book that should be available in every pathology department where there is an interest in these cells.'
The Journal of Clinical Pathology (July 1986)
`These two large volumes contain the proceedings of the Third Conference on Mononuclear Phagocytes held in Leiden in September 1978. They contain a wealth of material which will be of value to those working with monocytes. These books contain papers on the structure, cytochemistry, origin and maturation, function and plasma membranes of the monocyte, their antimicrobial role, and role in the immune response. It should prove valuable as a source of reference and information in this important developing field.'
British Journal of Haematology, 47 (1981)
`...containing the meeting discussions as well as the reports, these proceedings surely embrace the 1978 'state of knowledge' with respect to the mononuclear phagocytic systems.'
Experimental Hematology, 9:1 (1981)
`The reticuloendothelial system died in Leiden in 1969 at the hands of Ralph van Furth and from iets ashes sprang the mononuclear phagocytes system. This massive two volume proceedings from the 3rd Leiden conference held in 1978 is a tribute to the vigour of this new phoenix and clearly documents its explosive growth. Nearly two thousand pages of erudite and informative papers and reviews describing the functional properties of macrophages are enclosed... The contents are entirely comprehensive covering a bewildering range of functional attributes of these remarkable cells. Until superseded by the proceedings of the fourth Leiden conference (and what a prospect that is!) these two volumes will undoubtedly become the definitive text for anyone interested in mononuclear phagocytes.'
Journal of Clinical Pathology (May 1981)
`For those interested in the occult mysteries and properties of one of the most fascinating but difficult cell series to trace in origin and function, this two-volume series on mononuclear phagocytes will prove exceptionally interesting. It is a relatively complete chronicle of the progress made over the past decade in elucidating the function and stem cell origin of renewing populations of mononuclear phagocytes and related cells. The two volumes will prove useful as references for both teaching and research.'
American Journal of Veterinary Research, 42 (1981)
`These two volumes constitute an important landmark in the study of 'inflammation'. ...well produced and should be of value, not only to cellular pathologists and scientists, but also to all of us concerned with human diseases.'
Journal of the European Society of Pathology (October 1980)