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Mitochondrial Function In Vivo Evaluated by NADH Fluorescence de Avraham Mayevsky

Mitochondrial Function In Vivo Evaluated by NADH Fluorescence

Autor Avraham Mayevsky
en Limba Engleză Hardback – iul 2015
This book covers both the technological development and biomedical applications of NADH fluorescence. Topics covered include perspectives on the history of monitoring NADH fluorescence, the relationship between mitochondrial function and other functions at the tissue level, responses of NADH to physiological and pathophysiological conditions, monitoring of NADH in the human brain and other organs, and metabolism. It also includes an in-depth look at flavoprotein (Fp) fluorescence and NADH in relation to redox state. This is an ideal book for biomedical engineers, researchers, and graduate students interested in learning the biomedical applications of NADH fluorescence.
This book also:
  • Covers multisite monitoring of NADH, as well as multiparametric responses of NADH to physiological and pathophysiological conditions, and monitoring of various organs in various animal models
  • Describes the relationship between brain activation (i.e. epileptic activity and cortical spreading depression) and NADH redox state
  • Presents the effects of hypoxia,hyperbaric hyperoxia, and ischemia on brain NADH fluorescence and other tissue physiological parameters
 
About the Author
Avraham Mayevsky, Ph.D. is a Professor Emeritus in theFaculty of Life Sciences and the Brain Research Center at Bar Ilan University, Israel.
He has published  more than two hundred papers in the field of mitochondrial function and tissue physiology in vivo under pathophysiological conditions.
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Specificații

ISBN-13: 9783319166810
ISBN-10: 3319166816
Pagini: 292
Ilustrații: XIV, 276 p. 234 illus., 63 illus. in color.
Dimensiuni: 215 x 285 x 22 mm
Greutate: 0.89 kg
Ediția:2015
Editura: Springer
Locul publicării:Cham, Switzerland

Public țintă

Research

Cuprins

1. Introduction.- 2. Tissue Energy Metabolism and Mitochondrial Function.- 3. Spectroscopic monitoring of NADH – Historical Overview.- 4. Technological aspects of NADH monitoring In Vivo.- 5. Monitoring of NADH together with other tissue physiological parameters.- 6. Multisite Monitoring of NADH.- 7. Responses of NADH to physiological and pathophysiological conditions.- 8. Monitoring of various organs in various animal models.- 9. Monitoring of NADH in Human brain and body organs.- 10. Discussion.- Index.

Recenzii

“This is a great book conctning t history,physiology of multiple organs responses to normoxia, hypoxia, ischemic,hyperoxia, & hyperbaric conditions in anesthetized, awake, mammalsincluding humans. … I recommend this book for historians of Physiology,researchers in Neurology, neurosurgeons and students of Physiology.” (Joseph J.Grenier, Amazon.com, November, 2015)

Notă biografică

Prof. Avraham Mayevsky is a Professor Emeritus in The Mina & Everard Goodman Faculty of Life Sciences and the Leslie and Susan Gonda Multidisciplinary Brain Research Center at Bar-Ilan University in Ramat-Gan, Israel. Prof. Avraham Mayevsky's field of research since he started his Post-Doc training with Prof. Britton Chance in 1972, was Energy metabolism, including mitochondrial function in vivo, of the brain mainly and other tissues In Vivo, exposed to various pathophysiological conditions. During the 50 years of activity he was able to accomplish a large number of goals that have a very significant impact on the understanding of pathophysiological processes in the brain and other organs evaluated under In Vivo conditions. His vision was to develop experimental approaches and tools that will enable him to study various physiological processes in experimental animals and at the same time, will be ready for clinical applications.

Textul de pe ultima copertă

This book covers both the technological development and biomedical applications of NADH fluorescence. Topics covered include perspectives on the history of monitoring NADH fluorescence, the relationship between mitochondrial function and other functions at the tissue level, responses of NADH to physiological and pathophysiological conditions, monitoring of NADH in the human brain and other organs, and metabolism. It also includes an in-depth look at flavoprotein (Fp) fluorescence and NADH in relation to redox state. This is an ideal book for biomedical engineers, researchers, and graduate students interested in learning the biomedical applications of NADH fluorescence.
This book also:
  • Covers multisite monitoring of NADH, as well as multiparametric responses of NADH to physiological and pathophysiological conditions, and monitoring of various organs in various animal models
  • Describes the relationship between brain activation (i.e. epileptic activity and cortical spreading depression) and NADH redox state
  • Presents the effects of hypoxia, hyperbaric hyperoxia, and ischemia on brain NADH fluorescence and other tissue physiological parameters
  
About the Author
Avraham Mayevsky, Ph.D. is a Professor Emeritus in the Faculty of Life Sciences and the Brain Research Center at Bar Ilan University, Israel.
He has published  more than two hundred papers in the field of mitochondrial function and tissue physiology in vivo under pathophysiological conditions.

Caracteristici

Describes the subject matter in detail citing most of the 700 published papers in this field
Presents the relationship between mitochondrial function and other functions at the tissue level
Presents optical monitoring at the human level