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Metabolomics

Editat de Justin S. Knapp, William L. Cabrera
en Limba Engleză Hardback – 4 mai 2011
Metabolomics is the logical progression of the study of genes, transcripts and proteins. Nutrients, gut microbial metabolites and other bioactive food constituents interact with the body at system, organ, cellular and molecular levels, and effect the expression of genome at several levels, and subsequently, the production of metabolites. This book presents an overview of nutrigenomics and metabolomics tools, and their perspective in livestock health and production. In addition, this book describes how lists of masses (molecular ions) and mass unit bins of interest are searched within online databases for compound identification, the extra biochemical data required for metabolite confirmation, how data are visualised and what the putative and protein sequences are associated with observed metabolic changes. Moreover, environmental metabolomics is the application of metabolomics to the investigation of both free-living organisms directly obtained from the natural environment or laboratory conditions. This book outlines some of the advances made in areas of plant environmental metabolomics. The applications of microbial metagenomics, the use of genomics techniques to the study of communities of directly in their diverse natural environments, are explored as well. Other chapters examine the abnormalities in metabolism of cancer cells, which could play a strategic role in tumour initiation and behaviour.
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Specificații

ISBN-13: 9781616680060
ISBN-10: 1616680067
Pagini: 263
Ilustrații: diagrams,graphs
Dimensiuni: 183 x 258 x 21 mm
Greutate: 0.73 kg
Ediția:New.
Editura: Nova Science Publishers Inc

Cuprins

Preface; Correlations & Distances-Based Approaches to Static Analysis of the Variability in Metabolomic Datasets: Applications & Comparisons with Other Static & Kinetic Approaches; Metabolomic Profile & Fractal Dimensions in Breast Cancer Cells; Plant Environmental Metabolomics; Microbial Metagenomics: Concept, Methodology & Prospects for Novel Biocatalysts & Therapeutics from the Mammalian Gut Microbiome; Metabolite Identification, Pathways & Omic Integration using Online Databases & Tools; Nutrigenomics, Metabolomics & Metabonomics: Emerging Faces of Molecular Genomics & Nutrition; Machine Reconstruction of Metabolic Networks from Metabolomic Data through Symbolic-Statistical Learning; Metabolomics; The Role of Specific Estrogen Metabolites in the Initiation of Breast & Other Human Cancers; Index.